Selenoprotein R Antibody (QA-V7): sc-135558

Selenoprotein R Antibody (QA-V7) is a mouse monoclonal IgG1 kappa light chain antibody that detects the Selenoprotein R protein of human origin by western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). Anti-Selenoprotein R antibody (QA-V7) is available as a non-conjugated format. Selenoprotein R, also known as methionine-R-sulfoxide reductase or Selenoprotein X1, is a crucial zinc-binding protein that plays a significant role in cellular defense against oxidative stress. Selenoprotein R contains selenocysteine, which is encoded by the UGA stop codon, allowing participation in redox reactions that mitigate damage from reactive oxygen species. The presence of selenocysteine in Selenoprotein R′s structure enhances the ability to reduce oxidized methionine residues, thereby maintaining protein function and cellular integrity. The gene encoding Selenoprotein R features SECIS elements that facilitate proper incorporation of selenocysteine during translation, ensuring functionality in various biological processes. The importance of Selenoprotein R in protecting cells from oxidative damage underscores potential as a therapeutic target in conditions associated with oxidative stress, making Selenoprotein R (QA-V7) antibody an essential tool for researchers studying this critical protein.

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Selenoprotein R Antibody (QA-V7) References:

1. New mammalian selenocysteine-containing proteins identified with an algorithm that searches for selenocysteine insertion sequence elements.  |  Kryukov, GV., et al. 1999. J Biol Chem. 274: 33888-97. PMID: 10567350
2. Selenoprotein R is a zinc-containing stereo-specific methionine sulfoxide reductase.  |  Kryukov, GV., et al. 2002. Proc Natl Acad Sci U S A. 99: 4245-50. PMID: 11929995
3. Human selenoproteins at a glance.  |  Gromer, S., et al. 2005. Cell Mol Life Sci. 62: 2414-37. PMID: 16231092
4. Conserved nucleotide sequences in the open reading frame and 3' untranslated region of selenoprotein P mRNA.  |  Hill, KE., et al. 1993. Proc Natl Acad Sci U S A. 90: 537-41. PMID: 8421687
5. Multiple forms of selenoprotein P in rat plasma.  |  Chittum, HS., et al. 1996. Arch Biochem Biophys. 325: 124-8. PMID: 8554336
6. Human selenoprotein P gene maps to 5q31.  |  Hill, KE., et al. 1996. Genomics. 36: 550-1. PMID: 8884283

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Selenoprotein R Antibody (QA-V7) has 1 citations in a variety of scientific publications.

Primary antibodies like Anti-Selenoprotein R Antibody (QA-V7) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Selenoprotein R Antibody (QA-V7) Specifications

Alternate Product Name: Selenoprotein R

Product Clone Name: QA-V7

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids: 1-85

Epitope Target: Selenoprotein R

Epitope Species: human

Product Reactivity/Detection: Selenoprotein R

Species Reactivity/Detection: human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, ELISA

Vialing Information: Each vial contains 100 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 1 citations in various scientific publications

Available Conjugates/Forms for Selenoprotein R Antibody (QA-V7): N/A