Date published: 2026-5-12

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Seleno-L-cystine (CAS 29621-88-3)

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Alternate Names:
L-Selenocystine; (R,R)-3,3′-Diseleno-bis(2-aminopropionic acid)
CAS Number:
29621-88-3
Purity:
≥97%
Molecular Weight:
334.09
Molecular Formula:
C6H12N2O4Se2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Seleno-L-cystine, characterized by its diselenide-bridged structure among amino acids, plays a pivotal role in the realm of synthetic chemistry, particularly in the generation of selenylated diamino acids that are not found in nature. This compound distinguishes itself from selenocysteine (Sec) by its unique structural configuration, where two selenium atoms are integrated into a single molecular framework, setting a stark contrast to the singular selenium atom in Sec. The redox-active nature of Seleno-L-cystine allows it to engage in electron transfer processes, enabling it to function both as an antioxidant, where it can donate electrons to neutralize reactive oxygen species, and as a pro-oxidant, under conditions where it can accept electrons, thus contributing to the generation of reactive species under certain experimental setups.


Seleno-L-cystine (CAS 29621-88-3) References

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  2. Nonchromatographic speciation of selenium in edible oils using dispersive liquid-liquid microextraction and electrothermal atomic absorption spectrometry.  |  López-García, I., et al. 2013. J Agric Food Chem. 61: 9356-61. PMID: 24011330
  3. Crystal structure of seleno-l-cystine di-hydro-chloride.  |  Görbitz, CH., et al. 2015. Acta Crystallogr E Crystallogr Commun. 71: 726-9. PMID: 26090162
  4. Synthesis of Nanovesicular Glutathione Peroxidase Mimics with a Selenenylsulfide-Bearing Lipid.  |  Haratake, M., et al. 2016. ACS Omega. 1: 58-65. PMID: 30023472
  5. Micronutrients Selenomethionine and Selenocysteine Modulate the Redox Status of MCF-7 Breast Cancer Cells.  |  Pons, DG., et al. 2020. Nutrients. 12: PMID: 32213883
  6. Determination of Selenium Species in Muscle, Heart, and Liver Tissues of Lambs Using Mass Spectrometry Methods.  |  Gawor, A., et al. 2020. Animals (Basel). 10: PMID: 32392714
  7. Species-Specific, pH-Independent, Standard Redox Potential of Selenocysteine and Selenocysteamine.  |  Pálla, T., et al. 2020. Antioxidants (Basel). 9: PMID: 32492814
  8. Review on Sublethal Effects of Environmental Contaminants in Honey Bees (Apis mellifera), Knowledge Gaps and Future Perspectives.  |  Di Noi, A., et al. 2021. Int J Environ Res Public Health. 18: PMID: 33672936
  9. Potential of microalgae as source of health-beneficial bioactive components in produced eggs.  |  Jiru, M., et al. 2021. J Food Sci Technol. 58: 1-10. PMID: 34538889
  10. New Method for Simultaneous Arsenic and Selenium Speciation Analysis in Seafood and Onion Samples.  |  Karaś, K., et al. 2021. Molecules. 26: PMID: 34684804
  11. Selenomethionine-Dominated Selenium-Enriched Peanut Protein Ameliorates Alcohol-Induced Liver Disease in Mice by Suppressing Oxidative Stress.  |  Gao, L., et al. 2021. Foods. 10: PMID: 34945529
  12. Selective ferroptosis vulnerability due to familial Alzheimer's disease presenilin mutations.  |  Greenough, MA., et al. 2022. Cell Death Differ. 29: 2123-2136. PMID: 35449212
  13. Fluorinated diselenide nanoparticles for radiosensitizing therapy of cancer.  |  Vetrik, M., et al. 2022. Free Radic Biol Med. 187: 132-140. PMID: 35618181

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Seleno-L-cystine, 250 mg

sc-255609
250 mg
$123.00