Molecular structure of Sedaxane, CAS Number: 874967-67-6
Sedaxane (CAS 874967-67-6)
Alternate Names:
N-(2-Bicyclopropyl-2-ylphenyl)-3-difluoromethyl-1-methyl-1H-pyrazol-4-carboxylic Acid Amide
Application:
Sedaxane is a fungal respiration inhibitor
CAS Number:
874967-67-6
Molecular Weight:
331.36
Molecular Formula:
C18H19F2N3O
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Sedaxane is a fluorinated pyrazole compound that acts as a broad-range fungicide by binding to the succinate dehydrogenase complex in the fungal mitochondrium which, in turn, inhibits fungal respiration. This leads to the disruption of the energy supply to the fungal cell and ultimately causes its death. Sedaxane is applied as a seed treatment or a foliar spray and has shown high efficacy against a variety of plant pathogens. It is an aromatic amide, an organofluorine compound, a member of pyrazoles, a ring assembly and a member of cyclopropanes.
Sedaxane (CAS 874967-67-6) References
- Mutagenesis and functional studies with succinate dehydrogenase inhibitors in the wheat pathogen Mycosphaerella graminicola. | Scalliet, G., et al. 2012. PLoS One. 7: e35429. PMID: 22536383
- Biological activity of sedaxane---a novel broad-spectrum fungicide for seed treatment. | Zeun, R., et al. 2013. Pest Manag Sci. 69: 527-34. PMID: 23044852
- Sedaxane, Isopyrazam and Solatenol™: Novel Broad-spectrum Fungicides Inhibiting Succinate Dehydrogenase (SDH) - Synthesis Challenges and Biological Aspects. | Walter, H., et al. 2015. Chimia (Aarau). 69: 425-34. PMID: 26507595
- Bioinspired Synthesis of a Sedaxane Metabolite Using Catalytic Vanadyl Acetylacetonate and Molecular Oxygen. | Tyagi, S., et al. 2015. J Org Chem. 80: 11941-7. PMID: 26619065
- Sedaxicenes: potential new antifungal ferrocene-based agents? | Rubbiani, R., et al. 2016. Dalton Trans. 45: 6619-26. PMID: 26964501
- Altered gene expression by sedaxane increases PSII efficiency, photosynthesis and growth and improves tolerance to drought in wheat seedlings. | Ajigboye, OO., et al. 2017. Pestic Biochem Physiol. 137: 49-61. PMID: 28364804
- Sedaxane, Isopyrazam and Solatenol™: Novel Broad-spectrum Fungicides Inhibiting Succinate Dehydrogenase (SDH) - Synthesis Challenges and Biological Aspects. | Walter, H., et al. 2015. Chimia (Aarau). 69: 425-434. PMID: 28482975
- Sedaxane-Use of Nuclear Receptor Transactivation Assays, Toxicogenomics, and Toxicokinetics as Part of a Mode of Action Framework for Rodent Liver Tumors. | Peffer, RC., et al. 2018. Toxicol Sci. 162: 582-598. PMID: 29244179
- Biostimulant Effects of Seed-Applied Sedaxane Fungicide: Morphological and Physiological Changes in Maize Seedlings. | Dal Cortivo, C., et al. 2017. Front Plant Sci. 8: 2072. PMID: 29270181
- Leaching and sorption of neonicotinoid insecticides and fungicides from seed coatings. | Smalling, KL., et al. 2018. J Environ Sci Health B. 53: 176-183. PMID: 29286873
- The embryonic developmental effect of sedaxane on zebrafish (Danio rerio). | Yao, H., et al. 2018. Chemosphere. 197: 299-305. PMID: 29360593
- Sensitivity of Rhizoctonia solani to Succinate Dehydrogenase Inhibitor and Demethylation Inhibitor Fungicides. | Ajayi-Oyetunde, OO., et al. 2017. Plant Dis. 101: 487-495. PMID: 30677351
- Seed Treatment Effects on Maize Seedlings Coinfected with Rhizoctonia solani and Pratylenchus penetrans. | da Silva, MP., et al. 2017. Plant Dis. 101: 957-963. PMID: 30682922
- Real-Time PCR Assay for Detection of Sphacelotheca reiliana Infection in Maize (Zea mays) Seedlings and Evaluation of Seed Treatment Efficacy. | Anderson, SJ., et al. 2015. Plant Dis. 99: 1847-1852. PMID: 30699512
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Sedaxane, 25 mg | sc-473290 | 25 mg | $413.00 |