Date published: 2026-4-27

1-800-457-3801

SCBT Portrait Logo
Seach Input

Secoisolariciresinol (CAS 29388-59-8)

0.0(0)
Write a reviewAsk a question

See product citations (1)

Alternate Names:
(2R*,3R*)-2,3-Bis(4-hydroxy-3-methoxybenzyl)-1,4-butanediol
Application:
Secoisolariciresinol is a flaxseed lignan
CAS Number:
29388-59-8
Purity:
≥95%
Molecular Weight:
362.42
Molecular Formula:
C20H26O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

Secoisolariciresinol is a lignan compound that functions as a phytoestrogen in experimental applications. It interacts with estrogen receptors in a manner that modulates estrogenic activity, potentially influencing gene expression and cellular responses. Secoisolariciresinol may also participate in antioxidant and anti-inflammatory processes, contributing to its potential impact on cellular function. In experiment, secoisolariciresinol′s mechanism of action involves its ability to interact with estrogen receptors and influence downstream signaling pathways.


Secoisolariciresinol (CAS 29388-59-8) References

  1. Studies on the metabolism of the plant lignans secoisolariciresinol and matairesinol.  |  Niemeyer, HB., et al. 2003. J Agric Food Chem. 51: 6317-25. PMID: 14518962
  2. Secoisolariciresinol and isotaxiresinol inhibit tumor necrosis factor-alpha-dependent hepatic apoptosis in mice.  |  Banskota, AH., et al. 2004. Life Sci. 74: 2781-92. PMID: 15043992
  3. Secoisolariciresinol and matairesinol of sea buckthorn (Hippophaë rhamnoides L.) berries of different subspecies and harvesting times.  |  Yang, B., et al. 2006. J Agric Food Chem. 54: 8065-70. PMID: 17032010
  4. Bacterial conversion of secoisolariciresinol and anhydrosecoisolariciresinol.  |  Struijs, K., et al. 2009. J Appl Microbiol. 107: 308-17. PMID: 19302311
  5. The antidepressant effect of secoisolariciresinol, a lignan-type phytoestrogen constituent of flaxseed, on ovariectomized mice.  |  Wang, YF., et al. 2013. J Nat Med. 67: 222-7. PMID: 22476613
  6. Production of secoisolariciresinol from defatted flaxseed by bacterial biotransformation.  |  Li, MX., et al. 2012. J Appl Microbiol. 113: 1352-61. PMID: 22924993
  7. Hemorheological effects of secoisolariciresinol in ovariectomized rats.  |  Maslov, MY., et al. 2016. Biorheology. 53: 23-31. PMID: 26756280
  8. In silico and in vitro identification of secoisolariciresinol as a re-sensitizer of P-glycoprotein-dependent doxorubicin-resistance NCI/ADR-RES cancer cells.  |  Morsy, MA., et al. 2020. PeerJ. 8: e9163. PMID: 32566390
  9. Kraft Process-Formation of Secoisolariciresinol Structures and Incorporation of Fatty Acids in Kraft Lignin.  |  Lahtinen, MH., et al. 2021. J Agric Food Chem. 69: 5955-5965. PMID: 34006113
  10. Oral Pharmacokinetics of Enriched Secoisolariciresinol Diglucoside and Its Polymer in Rats.  |  Yang, X., et al. 2021. J Nat Prod. 84: 1816-1822. PMID: 34043363
  11. Comment on Kraft Process─Formation of Secoisolariciresinol Structures and Incorporation of Fatty Acids in Kraft Lignin.  |  Faleva, AV. 2022. J Agric Food Chem. 70: 5458-5459. PMID: 35442664
  12. Correction to Kraft Process─Formation of Secoisolariciresinol Structures and Incorporation of Fatty Acids in Kraft Lignin.  |  Lahtinen, MH., et al. 2022. J Agric Food Chem. 70: 5460-5461. PMID: 35471030
  13. Secondary metabolite pathway of SDG (secoisolariciresinol) was observed to trigger ROS scavenging system in response to Ca2+ stress in cotton.  |  Feng, X., et al. 2022. Genomics. 114: 110398. PMID: 35675878
  14. GC-MS/MS Quantification of EGFR Inhibitors, β-Sitosterol, Betulinic Acid, (+) Eriodictyol, (+) Epipinoresinol, and Secoisolariciresinol, in Crude Extract and Ethyl Acetate Fraction of Thonningia sanguinea.  |  Elhady, SS., et al. 2022. Molecules. 27: PMID: 35807354

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Secoisolariciresinol, 5 mg

sc-255608
5 mg
$226.00