seco Rapamycin Sodium Salt (CAS 148554-65-8)

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Alternate Names:

[2R-[2α,2(S*),3α,6β[2S*,3E,5E,7E,9S*,11R*,13R*,14R*,15E,17R*,19E/Z,21R*,22(1S*,3R*,4R*)]]]-1-[Oxo[tetrahydro-2-hydroxy-6-[14-hydroxy-22-(4-hydroxy-3-methoxycyclohexyl)-2,13-dimethoxy-3,9,11,15,17,21-hexamethyl-12,18-dioxo-3,5,7,15,19-docosapentaenyl]-3-methyl-2H-pyran-2-yl]acetyl]-2-piperidinecarboxylic Acid Monosodium Salt

Application:

seco Rapamycin Sodium Salt is a decomposition product of Rapamycin

CAS Number:

148554-65-8

Purity:

≥80%

Molecular Weight:

936.15

Molecular Formula:

C₅₁H₇₈NO₁₃•Na

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

* Refer to Certificate of Analysis for lot specific data.

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SDS & Certificate of Analysis

seco Rapamycin Sodium Salt inhibits the activity of the mammalian target of rapamycin (mTOR) protein. It binds to the FK506-binding protein 12 (FKBP12) and forms a complex that directly interacts with mTOR, leading to the inhibition of its kinase activity. This ultimately disrupts the mTOR signaling pathway, which is involved in the regulation of cellular processes such as cell growth, proliferation, and survival. By inhibiting mTOR, seco seco Rapamycin Sodium Salt affects the translation of specific mRNAs and the expression of genes that are for cell cycle progression and metabolism. It induces autophagy, a cellular process that degrades and recycles damaged organelles and proteins. seco Rapamycin Sodium Saltplays a critical role in modulating cellular processes and pathways by targeting the mTOR signaling pathway.