Sec6 Antibody (B-10): sc-271555
- Sec6 Antibody (B-10) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against amino acids 41-270 mapping near the N-terminus of Sec6 of human origin
- recommended for detection of Sec6 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including canine
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for Sec6 Antibody (B-10) for WB applications. These reagents are now offered in bundles with Sec6 Antibody (B-10) (see ordering information below).
Sec6 Antibody (B-10) is a mouse monoclonal IgG1 antibody that detects Sec6 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Sec6 is a crucial component of the mammalian exocyst complex, which consists of eight protein subunits, including Sec3, Sec5, Sec6, Sec8, Sec10, Sec15, Exo70, and Exo84. This complex plays a vital role in the targeting of exocytic vesicles to specific docking sites on the plasma membrane, thereby regulating polarized secretion in a GTP-dependent manner. Proper functioning of Sec6 is essential for maintaining cellular processes such as secretion and membrane trafficking, which are critical for various physiological functions, including cell signaling and nutrient uptake. Additionally, Sec6 is located on chromosome 5p15.33 in humans, highlighting its genetic significance. Sec6 (B-10) antibody serves as an invaluable tool for researchers studying the dynamics of exocytosis and its implications in cellular health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Sec6 Antibody (B-10) | sc-271555 | 200 µg/ml | $316.00 | |||
Sec6 Antibody (B-10): m-IgG Fc BP-HRP Bundle | sc-540248 | 200 µg Ab; 10 µg BP | $354.00 | |||
Sec6 Antibody (B-10): m-IgG1 BP-HRP Bundle | sc-541997 | 200 µg Ab; 20 µg BP | $354.00 |