Se51.9 Antibody (C-7): sc-377241

Se51.9 Antibody (C-7) is a mouse monoclonal IgG1 antibody that detects surface protein Se51.9 of Streptococcus equi by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-Se51.9 antibody (C-7) recognizes a 237 amino acid protein that plays a crucial role in the interaction between the pathogen and the host, making Se51.9 a potential biomarker for serodiagnosis and a candidate for subunit vaccine development. Surface protein Se51.9 is integral to the pathogenicity of Streptococcus equi subspecies equi, which is a clonal, equine host-adapted pathogen responsible for the highly contagious disease known as strangles. Strangles is characterized by severe tonsillitis and lymphadenitis, leading to symptoms such as fever, depression, and significant swelling of the lymph nodes in the head and neck, which can result in respiratory distress. The infection is primarily transmitted through inhalation of the bacteria or direct contact with the mucopurulent discharge from infected animals. Understanding the function of Se51.9 is vital, as Se51.9 not only aids in the diagnosis and treatment of strangles but also provides insights into the mechanisms of bacterial pathogenesis and host interaction, paving the way for the development of effective vaccines and therapeutic strategies.

The preferred Se51.9 antibody is Se51.9 Antibody (F-2): sc-377239.