Date published: 2026-4-25

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SDZ 205-557 hydrochloride (CAS 137196-67-9)

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Alternate Names:
4-Amino-5-chloro-2-methoxybenzoic acid 2-(diethylamino)ethyl ester hydrochloride
Application:
SDZ 205-557 hydrochloride is a SR-3 and SR-4 antagonist
CAS Number:
137196-67-9
Purity:
>99%
Molecular Weight:
337.25
Molecular Formula:
C14H21ClN2O3•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Available in US only.
* Refer to Certificate of Analysis for lot specific data.

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SDZ 205-557 hydrochloride acts as a SR-3 and SR-4 antagonist.


SDZ 205-557 hydrochloride (CAS 137196-67-9) References

Buchheit et al (1992) SDZ 205-557, a selective, surmountable antagonist for 5-HT4 receptors in the isolated guinea pig ileum. Naunyn-Schmied.Arch.Pharmacol. 345 387. Eglen et al (1993) The action of SDZ 205,557 at 5-hydroxytryptamine (5-HT3 and 5-HT4) receptors. Br.J.Pharmacol. 108 376. McMahon and Cunningham (1999) Antagonism of 5-hydroxytryptamine(4) receptors attenuates hyperactivity induced by cocaine: putative role for 5-hydroxytryptamine(4) receptors in the nucleus accumbens shell. J.Pharmacol.Exp.Ther. 291 300.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

SDZ 205-557 hydrochloride, 10 mg

sc-204273
10 mg
$119.00
US: Only available in the US

SDZ 205-557 hydrochloride, 50 mg

sc-204273A
50 mg
$510.00
US: Only available in the US