Molecular structure of (−)-Scopolamine hydrochloride, CAS Number: 55-16-3
(−)-Scopolamine hydrochloride (CAS 55-16-3)
Alternate Names:
Hyoscine hydrochloride; Scopine tropate
Application:
(−)-Scopolamine hydrochloride is an antimuscarinic agent
CAS Number:
55-16-3
Purity:
≥90%
Molecular Weight:
339.81
Molecular Formula:
C17H21NO4•HCl
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
(−)-Scopolamine hydrochloride is extensively used in research studies focusing on its ability to bind to muscarinic acetylcholine receptors. This compound is valuable for exploring the neurological mechanisms related to acetylcholine neurotransmission, especially in studies of learning, memory, and neurological disorders. Research involving (−)-Scopolamine hydrochloride typically investigates its effects on central nervous system activities, providing insights into how muscarinic receptor antagonism influences various cognitive and motor functions. Additionally, it is used in experiments aimed at understanding the role of cholinergic systems in behavioral and physiological responses. Furthermore, (−)-Scopolamine hydrochloride serves as a tool in electrophysiological studies, helping to elucidate the pathways and effects of neurotransmitter modulation in neural circuits.
(−)-Scopolamine hydrochloride (CAS 55-16-3) References
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- Dehydroevodiamine.HCl prevents impairment of learning and memory and neuronal loss in rat models of cognitive disturbance. | Park, CH., et al. 2000. J Neurochem. 74: 244-53. PMID: 10617126
- Quantitative autoradiography of muscarinic cholinergic receptor binding in the rat brain: distinction of receptor subtypes in antagonist competition assays. | Frey, KA. and Howland, MM. 1992. J Pharmacol Exp Ther. 263: 1391-400. PMID: 1469641
- FRET-based nanobiosensor for detection of scopolamine in hairy root extraction of Atropa belladonna. | Bagheri, F., et al. 2017. Talanta. 164: 593-600. PMID: 28107978
- Comparison of pro-amnesic efficacy of scopolamine, biperiden, and phencyclidine by using passive avoidance task in CD-1 mice. | Malikowska, N., et al. 2017. J Pharmacol Toxicol Methods. 86: 76-80. PMID: 28412329
- Muscarinic receptor signaling contributes to atypical antipsychotic drug reversal of the phencyclidine-induced deficit in novel object recognition in rats. | Miyauchi, M., et al. 2017. J Psychopharmacol. 31: 1588-1604. PMID: 28946779
- The expression of G protein-coupled receptor kinase 5 and its interaction with dendritic marker microtubule-associated protein-2 after status epilepticus. | Zeng, X., et al. 2017. Epilepsy Res. 138: 62-70. PMID: 29080472
- Alterations in the Neurobehavioral Phenotype and ZnT3/CB-D28k Expression in the Cerebral Cortex Following Lithium-Pilocarpine-Induced Status Epilepticus: the Ameliorative Effect of Leptin. | Ni, H., et al. 2019. Biol Trace Elem Res. 187: 100-106. PMID: 29687372
- Matured hop bitter acids improve spatial working and object recognition memory via nicotinic acetylcholine receptors. | Fukuda, T., et al. 2019. Psychopharmacology (Berl). 236: 2847-2854. PMID: 31069423
- ENALAPRIL EFFECT ON GLUTATHIONE CHAIN OF THE ANTIOXIDANT SYSTEM OF THE BRAIN IN RATS WITH SCOPOLAMINE-INDUCED NEURODEGENERATION. | Kmet, O., et al. 2019. Georgian Med News. 97-101. PMID: 31418740
- A Selective M1 and M3 Receptor Antagonist, Penehyclidine Hydrochloride, Exerts Antidepressant-Like Effect in Mice. | Sun, X., et al. 2019. Neurochem Res. 44: 2723-2732. PMID: 31606838
- Scopolamine amnesia of passive avoidance: a deficit of information acquisition. | Rush, DK. 1988. Behav Neural Biol. 50: 255-74. PMID: 3202811
- A Novel Potent and Selective Histamine H3 Receptor Antagonist Enerisant: In Vitro Profiles, In Vivo Receptor Occupancy, and Wake-Promoting and Procognitive Effects in Rodents. | Hino, N., et al. 2020. J Pharmacol Exp Ther. 375: 276-285. PMID: 32862143
- BIOCHEMICAL AND MORPHOLOGICAL MARKERS OF EXPERIMENTAL SCOPOLAMINE-INDUCED NEURODEGENERATION AND THE EFFECT OF ENALAPRIL ON THEM. | Kmet, OG., et al. 2020. Wiad Lek. 73: 2114-2119. PMID: 33310932
- The Solid-State Structures Of (-)-Scopolamine Free Base, (-)-Scopolamine Methobromide, (-)-Scopolamine Hydrobromide Trihydrate, And Of The Pseudopolymorphic Forms Of (-)-Scopolamine Hydrochloride Anhydrate And 1.66hydrate | Robert Glaser, et al. 2000. Canadian Journal of Chemistry. 78: 2.
Inhibitor of:
mAChR M.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
(−)-Scopolamine hydrochloride, 1 g | sc-253544 | 1 g | $325.00 |