Molecular structure of Scopolamine, CAS Number: 51-34-3
Scopolamine (CAS 51-34-3)
See product citations (2)
Alternate Names:
(−)-Hyoscine
CAS Number:
51-34-3
Molecular Weight:
303.35
Molecular Formula:
C17H21NO4
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Product Citations
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
Scopolamine is an acetylcholine antagonist meaning it inhibits the action of the neurotransmitter acetylcholine in the central and the peripheral nervous system. It works by competitively inhibiting muscarinic receptors for acetylcholine, acting as a nonselective muscarinic antagonist. It is a tropane alkaloid that can be found in certain plants in the Solanaceae family, such as Henbane (Hyoscyamus niger), Jimsonweed (Datura stramonium), and Belladonna (Atropa belladonna). Scopolamine also interacts with 5-HT3 receptors, where it acts as a competitive antagonist.
Scopolamine (CAS 51-34-3) References
- Formation of scopolamine from N-butyl-scopolammonium bromide in cigarettes. | Frascht, M., et al. 2007. J Anal Toxicol. 31: 220-3. PMID: 17555646
- Galantamine reverses scopolamine-induced behavioral alterations in Dugesia tigrina. | Ramakrishnan, L., et al. 2014. Invert Neurosci. 14: 91-101. PMID: 24402079
- Microdialysis pharmacokinetic study of scopolamine in plasma, olfactory bulb and vestibule after intranasal administration. | Wei, Y., et al. 2016. Drug Deliv. 23: 263-8. PMID: 24865285
- Post-training scopolamine treatment induced maladaptive behavior in open field habituation task in rats. | Popović, N., et al. 2014. PLoS One. 9: e100348. PMID: 24936785
- Time course of scopolamine effect on memory consolidation and forgetting in rats. | Popović, M., et al. 2015. Neurobiol Learn Mem. 118: 49-54. PMID: 25460041
- The Combination of Scopolamine and Psychostimulants for the Prevention of Severe Motion Sickness. | Zhang, LL., et al. 2016. CNS Neurosci Ther. 22: 715-22. PMID: 27160425
- Low-dose systemic scopolamine disrupts context conditioning in rats. | Luyten, L., et al. 2017. J Psychopharmacol. 31: 667-673. PMID: 28417664
- Establishing zebrafish as a model to study the anxiolytic effects of scopolamine. | Hamilton, TJ., et al. 2017. Sci Rep. 7: 15081. PMID: 29118373
- Biotic elicitation for scopolamine production by hairy root cultures of Datura metel. | Shakeran, Z., et al. 2017. Mol Biol Res Commun. 6: 169-179. PMID: 29417086
- Diosmin is neuroprotective in a rat model of scopolamine-induced cognitive impairment. | Shabani, S. and Mirshekar, MA. 2018. Biomed Pharmacother. 108: 1376-1383. PMID: 30372840
- Differential effects of post-training scopolamine on spatial and non-spatial learning tasks in mice. | Thonnard, D., et al. 2019. Brain Res Bull. 152: 52-62. PMID: 31302239
- Studying the interaction of scopolamine with calf-thymus DNA: An in-vitro and in-silico approach and genotoxicity. | Ameen, F., et al. 2022. Spectrochim Acta A Mol Biomol Spectrosc. 265: 120391. PMID: 34571375
- Scopolamine intoxications. | Lauwers, LF., et al. 1983. Intensive Care Med. 9: 283-5. PMID: 6619397
Inhibitor of:
AChR, AChRα1, HMW-Guanylin, IMP-3, mAChR M1, mAChR M3, mAChR M4, mAChR M5, Olfr473, Olfr476, Olfr724, Olfr725, Olfr726, Olfr727, Olfr728, Olfr791, Olr34, SEZ6, SMGC, and Vmn2r48.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Scopolamine, 100 mg | sc-473216 | 100 mg | $172.00 | |||
Scopolamine, 500 mg | sc-473216A | 500 mg | $506.00 | |||
Scopolamine, 1 g | sc-473216B | 1 g | $786.00 |