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SC 26196 is a selective Δ6 desaturase inhibitor that displays selectivity over Δ5 and Δ9 desaturases.
1. Obukowicz, M G., et al., 1998. Novel, selective delta6 or delta5 fatty acid desaturase inhibitors as antiinflammatory agents in mice. The Journal of pharmacology and experimental therapeutics. 287(1): 157-66. PMID: 9765335
2. Hansen-Petrik, Melissa B., et al., 2002. Selective inhibition of Delta-6 desaturase impedes intestinal tumorigenesis. Cancer letters. 175(2): 157-63. PMID: 11741743
3. Zhang, Lei., et al., 2010. A multiplexed cell assay in HepG2 cells for the identification of delta-5, delta-6, and delta-9 desaturase and elongase inhibitors. Journal of biomolecular screening. 15(2): 169-76. PMID: 20086206
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