SC 2001 (CAS 1383727-17-0)
Alternate Names:
SC2001; SC-2001
CAS Number:
1383727-17-0
Molecular Weight:
367.03
Molecular Formula:
C18H14BrN3O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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SC 2001 (CAS 1383727-17-0) References
- Central control of body weight and appetite. | Woods, SC. and D'Alessio, DA. 2008. J Clin Endocrinol Metab. 93: S37-50. PMID: 18987269
- A novel obatoclax derivative, sc-2001, induces apoptosis in hepatocellular carcinoma cells through SHP-1-dependent STAT3 inactivation. | Chen, KF., et al. 2012. Cancer Lett. 321: 27-35. PMID: 22465052
- Inhibition of Bcl-2 improves effect of LCL161, a SMAC mimetic, in hepatocellular carcinoma cells. | Chen, KF., et al. 2012. Biochem Pharmacol. 84: 268-77. PMID: 22580047
- Obatoclax analog sc-2001 inhibits STAT3 phosphorylation through enhancing SHP-1 expression and induces apoptosis in human breast cancer cells. | Liu, CY., et al. 2014. Breast Cancer Res Treat. 146: 71-84. PMID: 24903225
- RFX1-dependent activation of SHP-1 induces autophagy by a novel obatoclax derivative in hepatocellular carcinoma cells. | Su, JC., et al. 2014. Oncotarget. 5: 4909-19. PMID: 24952874
- sc-2001 overcomes STAT3-mediated sorafenib resistance through RFX-1/SHP-1 activation in hepatocellular carcinoma. | Su, JC., et al. 2014. Neoplasia. 16: 595-605. PMID: 25047655
- RFX-1-dependent activation of SHP-1 inhibits STAT3 signaling in hepatocellular carcinoma cells. | Su, JC., et al. 2014. Carcinogenesis. 35: 2807-14. PMID: 25322871
- Use of a MCL-1 inhibitor alone to de-bulk melanoma and in combination to kill melanoma initiating cells. | Mukherjee, N., et al. 2017. Oncotarget. 8: 46801-46817. PMID: 27086916
- Differences in bovine parainfluenza 3 virus variants studied by sequencing of the genes of viral envelope proteins. | Shioda, T., et al. 1988. Virology. 162: 388-96. PMID: 2829426
- Alteration of SHP-1/p-STAT3 Signaling: A Potential Target for Anticancer Therapy. | Huang, TT., et al. 2017. Int J Mol Sci. 18: PMID: 28594363
Activator of:
p73.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
SC 2001, 50 mg | sc-507307 | 50 mg | $520.00 |