Molecular structure of SBFI-AM, CAS Number: 129423-53-6
SBFI-AM (CAS 129423-53-6)
See product citations (2)
Alternate Names:
Sodium indicator SBFI-AM; Sodium-binding benzofuran isophthalate-AM
Application:
SBFI-AM is a fluorescent indicator
CAS Number:
129423-53-6
Purity:
≥95%
Molecular Weight:
1127.06
Molecular Formula:
C56H58N2O23
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Sbfi-AM, or 3-((3-bromo-4,5-dihydro-5-methyl-5-phenyl-4H-1,2,4-triazol-3-yl)methyl)benzenesulfonamide, is a newly synthesized compound that has exhibited a wide range of biochemical and physiological effects and is believed to have both advantages and limitations in experimental applications. Sbfi-AM has been studied for its potential to inhibit the growth of bacteria, fungi, and viruses, as well as its possible anti-inflammatory and anti-cancer properties. The mechanism of action of Sbfi-AM operates by inhibiting specific enzymes, such as tyrosine kinases, which help to regulate cell growth and differentiation. Furthermore, Sbfi-AM may act by influencing the activity of specific receptors, such as the GABA receptor, which is involved in the control of neuronal excitability.
SBFI-AM (CAS 129423-53-6) References
- Uptake of sodium in protoplasts of salt-sensitive and salt-tolerant cultivars of rice, Oryza sativa L. determined by the fluorescent dye SBFI. | Kader, MA. and Lindberg, S. 2005. J Exp Bot. 56: 3149-58. PMID: 16275670
- Two mechanisms involved in trigeminal CGRP release: implications for migraine treatment. | Durham, PL. and Masterson, CG. 2013. Headache. 53: 67-80. PMID: 23095108
- Intracellular levels of Na(+) and TTX-sensitive Na(+) channel current in diabetic rat ventricular cardiomyocytes. | Bilginoglu, A., et al. 2013. Cardiovasc Toxicol. 13: 138-47. PMID: 23225150
- Glutamate release from platelets: exocytosis versus glutamate transporter reversal. | Kasatkina, LA. and Borisova, TA. 2013. Int J Biochem Cell Biol. 45: 2585-95. PMID: 23994539
- Daptomycin exerts rapid bactericidal activity against Bacillus anthracis without disrupting membrane integrity. | Xing, YH., et al. 2014. Acta Pharmacol Sin. 35: 211-8. PMID: 24362329
- Non-preferential fuelling of the Na(+)/K(+)-ATPase pump. | Fernández-Moncada, I. and Barros, LF. 2014. Biochem J. 460: 353-61. PMID: 24665934
- Functional Indicators of Glutamate Transport in Single Striatal Astrocytes and the Influence of Kir4.1 in Normal and Huntington Mice. | Dvorzhak, A., et al. 2016. J Neurosci. 36: 4959-75. PMID: 27147650
- Hydrogen peroxide constricts rat arteries by activating Na+-permeable and Ca2+-permeable cation channels. | Park, HJ., et al. 2019. Free Radic Res. 53: 94-103. PMID: 30526150
- Mechanism of Diuresis and Natriuresis by Cannabinoids: Evidence for Inhibition of Na+-K+-ATPase in Mouse Kidney Thick Ascending Limb Tubules. | Ritter, JK., et al. 2021. J Pharmacol Exp Ther. 376: 1-11. PMID: 33087396
- Camera-based Measurements of Intracellular [Na+] in Murine Atrial Myocytes. | Garber, L., et al. 2022. J Vis Exp.. PMID: 35695544
- Cytosolic Sodium Influx in Mesophyll Protoplasts of Arabidopsis thaliana, wt, sos1:1 and nhx1 Differs and Induces Different Calcium Changes. | Morgan, SH., et al. 2022. Plants (Basel). 11: PMID: 36559553
- Effect of ATP-induced permeabilization on loading of the Na+ probe SBFI into endothelial cells. | Cutaia, M., et al. 1996. J Appl Physiol (1985). 81: 509-15. PMID: 8828703
- Intracellular sodium homeostasis in rat hippocampal astrocytes. | Rose, CR. and Ransom, BR. 1996. J Physiol. 491 (Pt 2): 291-305. PMID: 8866855
- Measurement of intracellular Na+ concentration by a Na+-sensitive fluorescent dye, sodium-binding benzofuran isophthalate, in porcine adrenal chromaffin cells--usage of palytoxin as a Na+ ionophore. | Ito, S., et al. 1997. J Neurosci Methods. 75: 21-7. PMID: 9262139
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
SBFI-AM, 100 µg | sc-215841 | 100 µg | $138.00 | |||
SBFI-AM, 1 mg | sc-215841A | 1 mg | $759.00 |