Molecular structure of SBE 13 hydrochloride, CAS Number: 1052532-15-6
SBE 13 hydrochloride (CAS 1052532-15-6)
Application:
SBE 13 hydrochloride is a PLK1 selective inhibitor
CAS Number:
1052532-15-6
Purity:
≥98%
Molecular Weight:
479.40
Molecular Formula:
C24H27ClN2O4•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
Technical Information
Safety Information
SDS & Certificate of Analysis
SBE 13 hydrochloride is a selective inhibitor of PLK1 (IC50 values are 200 pM, 875 nM and 66 μM for PLK1, PLK3 and PLK2 respectively). SBE 13 hydrochloride targets the inactive conformation of PLK1, and exhibits no effect on Aurora kinase A activity. Binds and stabilizes the inactive form of PLK1. This compound delays cell cycle progression, reduces cell proliferation and induces apoptosis in a range of human cancer cell lines.
Inhibitor of:
Plk.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
SBE 13 hydrochloride, 5 mg | sc-362795 | 5 mg | $65.00 | |||
SBE 13 hydrochloride, 25 mg | sc-362795A | 25 mg | $352.00 |