Date published: 2025-11-1

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SB 699551 dihydrochloride (CAS 864741-95-7)

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Alternate Names:
N-[2-(Dimethylamino)ethyl]-N-[[4′-[[ (2-phenylethyl)amino]methyl][1,1′-biphenyl]-4-yl]me thyl]cyclopentanepropanamide dihydrochloride
Application:
SB 699551 is A receptor antagonist that is selective for SR-5
CAS Number:
864741-95-7
Purity:
≥98%
Molecular Weight:
584.66
Molecular Formula:
C34H45N3O•2HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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SB 699551 dihydrochloride functions as a selective antagonist of the orexin OX1 receptor. It acts by binding to the OX1 receptor and inhibiting the binding of orexin, thereby blocking the downstream signaling pathways activated by the receptor. SB 699551 dihydrochloride′s mechanism of action involves targeting the OX1 receptor and preventing its activation by endogenous orexin ligands. By doing so, SB 699551 dihydrochloride effectively modulates the activity of the orexin system, which plays a role in regulating various physiological processes. In a research and development setting, SB 699551 dihydrochloride can be used to investigate the specific functions of the orexin OX1 receptor and its involvement in various biological pathways.


SB 699551 dihydrochloride (CAS 864741-95-7) References

  1. The 5-HT5A receptor regulates excitability in the auditory startle circuit: functional implications for sensorimotor gating.  |  Curtin, PC., et al. 2013. J Neurosci. 33: 10011-20. PMID: 23761896

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

SB 699551 dihydrochloride, 5 mg

sc-361349
5 mg
$142.00

SB 699551 dihydrochloride, 25 mg

sc-361349A
25 mg
$797.00