Date published: 2025-11-16

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SB-668875 (CAS 274252-40-3)

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CAS Number:
274252-40-3
Molecular Weight:
2857.26
Molecular Formula:
C120H206N44O35S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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A novel, selective peptide agonist at OX2 orexin receptors. Possesses advantages over Orexins A and B which are equipotent at OX2 orexin receptors. The orexins can cause direct and reversible depolarisation of the postsynaptic membrane.


SB-668875 (CAS 274252-40-3) References

Soffin, E.M., et al., Pharmacological characterisation of the orexin receptor subtype mediating postsynaptic excitation in the rat dorsal raphe nucleus. Neuropharmacology 46, 1168-1176, (2004) Soffin, E. M. et al., Pharmacological characterisation of the orexin receptor subtype mediating postsynaptic excitation in the rat dorsal raphe nucleus Neuropharmacology 46, 1168-1176, (2004) Soffin, E. M. et al, SB-334867-A antagonises orexin mediated excitation in the locus coeruleus. Neuropharmacology 42, 127-133, (2002)

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

SB-668875, 1 mg

sc-255606
1 mg
$390.00