SB 271046 hydrochloride (CAS 209481-20-9)
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SB 271046 hydrochloride is a compound utilized in neuroscience and biochemical research, particularly for its role as a selective antagonist of the 5-HT6 receptor. In studies focusing on neurotransmission, SB 271046 hydrochloride helps to elucidate the function of serotoninergic systems by blocking the 5-HT6 receptor and observing the resultant effects on signal transduction pathways. The compound is also employed in research models to study cognitive processes, as the 5-HT6 receptor has been implicated in learning and memory. By using SB 271046 hydrochloride, researchers are able to investigate potential mechanisms underlying cognitive function and assess the involvement of serotonin receptors in these processes. Additionally, its use in certain experimental models provides insights into the role of 5-HT6 receptors in behavior and neural circuitry.
SB 271046 hydrochloride (CAS 209481-20-9) References
- Effects of the 5-HT(6) receptor antagonist, SB-271046, in animal models for schizophrenia. | Pouzet, B., et al. 2002. Pharmacol Biochem Behav. 71: 635-43. PMID: 11888555
- Co-administration of 5-HT6 receptor antagonists with clozapine, risperidone, and a 5-HT2A receptor antagonist: effects on prepulse inhibition in rats. | Fijał, K., et al. 2014. Psychopharmacology (Berl). 231: 269-81. PMID: 23954911
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
SB 271046 hydrochloride, 10 mg | sc-361343 | 10 mg | $193.00 | |||
SB 271046 hydrochloride, 50 mg | sc-361343A | 50 mg | $803.00 |