Molecular structure of SAR7334, CAS Number: 1333210-07-3
SAR7334 (CAS 1333210-07-3)
CAS Number:
1333210-07-3
Molecular Weight:
367.87
Molecular Formula:
C21H22ClN3O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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SAR7334 (CAS 1333210-07-3) References
- Discovery and pharmacological characterization of a novel potent inhibitor of diacylglycerol-sensitive TRPC cation channels. | Maier, T., et al. 2015. Br J Pharmacol. 172: 3650-60. PMID: 25847402
- Pharmacological Characterization of the Native Store-Operated Calcium Channels of Cortical Neurons from Embryonic Mouse Brain. | Chauvet, S., et al. 2016. Front Pharmacol. 7: 486. PMID: 28018223
- The ATP-gated P2X1 ion channel contributes to the severity of antibody-mediated Transfusion-Related Acute Lung Injury in mice. | El Mdawar, MB., et al. 2019. Sci Rep. 9: 5159. PMID: 30914724
- Activation of TRPC6 channels contributes to (+)-conocarpan-induced apoptotic cell death in HK-2 cells. | Yang, G., et al. 2019. Food Chem Toxicol. 129: 281-290. PMID: 31054997
- Ameliorated biomechanical properties of carotid arteries by puerarin in spontaneously hypertensive rats. | Fang, X., et al. 2021. BMC Complement Med Ther. 21: 173. PMID: 34154575
- The role of TRPC6 calcium channels and P2 purinergic receptors in podocyte mechanical and metabolic sensing. | Gyarmati, G., et al. 2021. Physiol Int.. PMID: 34978536
- Nonselective TRPC channel inhibition and suppression of aminoglycoside-induced premature termination codon readthrough by the small molecule AC1903. | Baradaran-Heravi, A., et al. 2022. J Biol Chem. 298: 101546. PMID: 34999117
- Structural mechanism of human TRPC3 and TRPC6 channel regulation by their intracellular calcium-binding sites. | Guo, W., et al. 2022. Neuron. 110: 1023-1035.e5. PMID: 35051376
- Activation of TRPC6 by AngⅡ Induces Podocyte Injury and Participates in Proteinuria of Nephrotic Syndrome. | Feng, Y., et al. 2022. Front Pharmacol. 13: 915153. PMID: 35991898
- TRPC6 inhibits renal tubular epithelial cell pyroptosis through regulating zinc influx and alleviates renal ischemia-reperfusion injury. | Shen, B., et al. 2022. FASEB J. 36: e22527. PMID: 36036542
- Puerarin ameliorates myocardial remodeling of spontaneously hypertensive rats through inhibiting TRPC6-CaN-NFATc3 pathway. | Yan, J., et al. 2022. Eur J Pharmacol. 933: 175254. PMID: 36087696
- Smooth Muscle Cells of Dystrophic (mdx) Mice Are More Susceptible to Hypoxia; The Protective Effect of Reducing Ca2+ Influx. | Uryash, A., et al. 2023. Biomedicines. 11: PMID: 36831159
- Inhibition and potentiation of the exercise pressor reflex by pharmacological modulation of TRPC6 in male rats. | Ducrocq, GP., et al. 2024. J Physiol.. PMID: 38340081
Inhibitor of:
C10orf63, Orai1, OTRPC4, TMEM86B, TRAPPC8, TRPC3, and TRPC4AP.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
SAR7334, 10 mg | sc-507445 | 10 mg | $510.00 |