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Saquayamycin B1 is a chemically intriguing member of the gilvocarcin group, known for its complex tetra-cyclic structure, usually derived from actinobacteria. This compound is particularly noted for its unique interaction with DNA, where it binds and, upon exposure to light, generates reactive oxygen species that cause DNA damage through the formation of adducts and strand breaks. This mechanism is pivotal in studies focused on the pathways of DNA damage and repair, offering insights into cellular responses to such stress without any therapeutic implications. In research settings, Saquayamycin B1 serves as a valuable tool to induce and study controlled DNA damage, helping to elucidate cellular repair mechanisms and the maintenance of genomic integrity, thereby deepening our understanding of molecular biology processes critical in maintaining cellular function and preventing mutagenesis.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Saquayamycin B1, 500 µg | sc-364135 | 500 µg | $147.00 | |||
Saquayamycin B1, 1 mg | sc-364135A | 1 mg | $227.00 |