Molecular structure of Salsolinol-1-carboxylic acid, CAS Number: 57256-34-5
Salsolinol-1-carboxylic acid (CAS 57256-34-5)
Alternate Names:
1-Methyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid
Application:
Salsolinol-1-carboxylic acid is an novel amino acid alkaloid endogenous to the CNS
CAS Number:
57256-34-5
Molecular Weight:
223.23
Molecular Formula:
C11H13NO4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Salsolinol-1-carboxylic acid is an amino acid that occurs naturally in the CNS. Salsolinol-1-carboxylic acid, an organic compound derived from salsolinol, is thought to play a role in regulating reward and addiction pathways in the brain. Research has been conducted to explore its potential involvement in various neurological and physiological processes.
Salsolinol-1-carboxylic acid (CAS 57256-34-5) References
- Contrasting effects of catecholic and O-methylated tetrahydroisoquinolines on hydroxyl radical production. | Nappi, AJ., et al. 1999. Biochim Biophys Acta. 1434: 64-73. PMID: 10556560
- beta-Carbolines and Tetrahydroisoquinolines: Detection and Function in Mammals. | Rommelspacher, H., et al. 1991. Planta Med. 57: S85-92. PMID: 17226228
- Identification of salsolinol in the mediobasal hypothalamus of lactating ewes and its relation to suckling-induced prolactin and GH release. | Misztal, T., et al. 2008. J Endocrinol. 198: 83-9. PMID: 18434346
- Interrelationship between activation of dopaminergic pathways and cerebrospinal fluid concentration of dopamine tetrahydroisoquinoline metabolite salsolinol in humans: preliminary findings. | Faraj, BA., et al. 1991. Alcohol Clin Exp Res. 15: 86-9. PMID: 2024737
- Elevation of plasma salsolinol sulfate in chronic alcoholics as compared to nonalcoholics. | Faraj, BA., et al. 1989. Alcohol Clin Exp Res. 13: 155-63. PMID: 2658649
- Racemic Salsolinol and its Enantiomers Act as Agonists of the μ-Opioid Receptor by Activating the Gi Protein-Adenylate Cyclase Pathway. | Berríos-Cárcamo, P., et al. 2016. Front Behav Neurosci. 10: 253. PMID: 28167903
- Isolation and Sequencing of Salsolinol Synthase, an Enzyme Catalyzing Salsolinol Biosynthesis. | Chen, X., et al. 2018. ACS Chem Neurosci. 9: 1388-1398. PMID: 29602279
- Not Just from Ethanol. Tetrahydroisoquinolinic (TIQ) Derivatives: from Neurotoxicity to Neuroprotection. | Peana, AT., et al. 2019. Neurotox Res. 36: 653-668. PMID: 31049880
- A secret that underlies Parkinson's disease: The damaging cycle. | Sun, F., et al. 2019. Neurochem Int. 129: 104484. PMID: 31173779
- Oxidative decarboxylation of salsolinol-1-carboxylic acid to 1,2-dehydrosalsolinol: evidence for exclusive catalysis by particulate factors in rat kidney. | Collins, MA. and Cheng, BY. 1988. Arch Biochem Biophys. 263: 86-95. PMID: 3369867
- Oxidation chemistry of the endogenous central nervous system alkaloid salsolinol-1-carboxylic acid. | Zhang, F. and Dryhurst, G. 1993. J Med Chem. 36: 11-20. PMID: 8421275
- A novel enzyme enantio-selectively synthesizes (R)salsolinol, a precursor of a dopaminergic neurotoxin, N-methyl(R)salsolinol. | Naoi, M., et al. 1996. Neurosci Lett. 212: 183-6. PMID: 8843103
- Synthesis of the R and S enantiomers of 1, 2, 3, 4-tetrahydro-6, 7-dihydroxy-1-methylisoquinoline-1-carboxylic acid | Dostert, P., Varasi, M., Della Torre, A., Monti, C., & Rizzo, V. 1992. European journal of medicinal chemistry. 27(1): 57-59.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Salsolinol-1-carboxylic acid, 10 mg | sc-204259 | 10 mg | $113.00 | |||
Salsolinol-1-carboxylic acid, 50 mg | sc-204259A | 50 mg | $480.00 |