Salmon Anemia Virus Antibody (18D8): sc-52218

Salmon Anemia Virus Antibody (18D8) is a mouse monoclonal IgG2b antibody that detects Salmon Anemia Virus in Salmon Anemia Virus by western blotting (WB). Salmon Anemia Virus (SAV) is a significant pathogen responsible for infectious salmon anemia (ISA), a viral disease that severely impacts Atlantic salmon (Salmo salar) populations, leading to high mortality rates. SAV is enveloped and ranges from 45 to 140 nm in diameter, with the ability to be cultured in the Atlantic salmon head kidney (SHK1) cell line, which is crucial for studying pathogenic mechanisms. SAV interacts with the host′s immune system by employing a receptor-destroying enzyme that facilitates entry into host cells via the endocytic pathway, similar to mechanisms used by the influenza virus. This ability to evade immune response is vital for SAV survival and propagation, making anti-SAV antibody (18D8) an essential tool for researchers aiming to understand the dynamics of SAV infection and effects on salmon health. Using SAV (18D8) antibody in western blotting (WB), scientists can effectively analyze the presence and expression levels of SAV proteins, contributing to the development of strategies for disease management and prevention in aquaculture.