Sall3 Antibody (A-9): sc-271818

Sall3 Antibody (A-9) is a mouse monoclonal IgG1 antibody that detects Sall3 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). anti-Sall3 antibody (A-9) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates, providing versatility for different experimental needs. Sall3 protein, also known as sal-like 3, plays a crucial role in embryonic development as a transcription regulator, influencing the expression of genes necessary for proper cellular differentiation and organogenesis. Notably, Sall3 is expressed in specific regions of the developing brain, including the hippocampus and thalamic nuclei, highlighting its importance in neurodevelopment. Sall3 protein′s ability to interact with other transcription factors and regulatory proteins is essential for orchestrating complex developmental processes, making Sall3 a significant focus of research in developmental biology and neurogenetics. Understanding the function and interactions of Sall3 can provide insights into various developmental disorders and potential therapeutic targets.

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Sall3 Antibody (A-9) References:

1. Zinc finger protein sall2 is not essential for embryonic and kidney development.  |  Sato, A., et al. 2003. Mol Cell Biol. 23: 62-9. PMID: 12482961
2. Tissue microarray validation of epidermal growth factor receptor and SALL2 in synovial sarcoma with comparison to tumors of similar histology.  |  Nielsen, TO., et al. 2003. Am J Pathol. 163: 1449-56. PMID: 14507652
3. Genetic determination of nephrogenesis: the Pax/Eya/Six gene network.  |  Brodbeck, S. and Englert, C. 2004. Pediatr Nephrol. 19: 249-55. PMID: 14673635
4. The Sall3 locus is an epigenetic hotspot of aberrant DNA methylation associated with placentomegaly of cloned mice.  |  Ohgane, J., et al. 2004. Genes Cells. 9: 253-60. PMID: 15005712
5. p150(Sal2) is a p53-independent regulator of p21(WAF1/CIP).  |  Li, D., et al. 2004. Mol Cell Biol. 24: 3885-93. PMID: 15082782
6. Identification of genes differentially expressed in testes containing carcinoma in situ.  |  Hoei-Hansen, CE., et al. 2004. Mol Hum Reprod. 10: 423-31. PMID: 15123780
7. Sall1, a causative gene for Townes-Brocks syndrome, enhances the canonical Wnt signaling by localizing to heterochromatin.  |  Sato, A., et al. 2004. Biochem Biophys Res Commun. 319: 103-13. PMID: 15158448
8. Identification of kidney mesenchymal genes by a combination of microarray analysis and Sall1-GFP knockin mice.  |  Takasato, M., et al. 2004. Mech Dev. 121: 547-57. PMID: 15172686
9. [Congenital fibrosis of extraocular muscles (CFEOM) and other phenotypes of congenital cranial dysinnervation syndromes (CCDD)].  |  Hanisch, F., et al. 2005. Nervenarzt. 76: 395-402. PMID: 15221064
10. Loss of the Sall3 gene leads to palate deficiency, abnormalities in cranial nerves, and perinatal lethality.  |  Parrish, M., et al. 2004. Mol Cell Biol. 24: 7102-12. PMID: 15282310
11. Novel mutations in the gene SALL4 provide further evidence for acro-renal-ocular and Okihiro syndromes being allelic entities, and extend the phenotypic spectrum.  |  Borozdin, W., et al. 2004. J Med Genet. 41: e102. PMID: 15286162
12. Mutations in SALL4 in malformed father and daughter postulated previously due to reflect mutagenesis by thalidomide.  |  Kohlhase, J. and Holmes, LB. 2004. Birth Defects Res A Clin Mol Teratol. 70: 550-1. PMID: 15329836
13. SALL4 deletions are a common cause of Okihiro and acro-renal-ocular syndromes and confirm haploinsufficiency as the pathogenic mechanism.  |  Borozdin, W., et al. 2004. J Med Genet. 41: e113. PMID: 15342710
14. No evidence of SALL4-mutations in isolated sporadic duane retraction 'syndrome' (DURS).  |  Wabbels, BK., et al. 2004. Am J Med Genet A. 131: 216-8. PMID: 15386473
15. [Clinical and molecular genetic findings in isolated sporadic Duane syndrome].  |  Wabbels, BK., et al. 2004. Klin Monbl Augenheilkd. 221: 849-53. PMID: 15499520

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Sall3 Antibody (A-9) has 1 citations in a variety of scientific publications.

Primary antibodies like Anti-Sall3 Antibody (A-9) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Sall3 Antibody (A-9) Specifications

Alternate Product Name: Sall3

Product Clone Name: A-9

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁

Amino Acids: 713-751

Epitope Target: Sall3

Epitope Species: human

Product Reactivity/Detection: Sall3

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: canine, porcine and avian

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgG₁ in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 1 citations in various scientific publications

Available Conjugates/Forms for Sall3 Antibody (A-9): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, P: Blocking Peptide, PE: Phycoerythrin, X: TransCruz Reagent