Molecular structure of Salinomycin Sodium Salt, CAS Number: 55721-31-8
Salinomycin Sodium Salt (CAS 55721-31-8)
Application:
Salinomycin Sodium Salt is A polyether ionophore antibiotic
CAS Number:
55721-31-8
Purity:
12% in Calcium Carbonate
Molecular Weight:
772.98
Molecular Formula:
C42H69NaO11
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Salinomycin is a polyether antibiotic that functions as an ionophore, facilitating the transport of monovalent cations across cell membranes. It acts as a potassium ionophore, disrupting the ion balance within cells. This disruption leads to the depolarization of mitochondrial membranes, ultimately inhibiting oxidative phosphorylation and ATP production. Salinomycin may induce apoptosis in cancer cells by interfering with various cellular processes, including the Wnt/β-catenin signaling pathway. This compound may inhibit the activity of ATP-binding cassette (ABC) transporters, which play a role in multidrug resistance in cancer cells. Salinomycin′s mode of action involves disrupting ion balance and mitochondrial function, as well as interfering with cellular signaling pathways and chemical resistance mechanisms.
Salinomycin Sodium Salt (CAS 55721-31-8) References
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- Corydaline and l-tetrahydropalmatine attenuate morphine-induced conditioned place preference and the changes in dopamine D2 and GluA1 AMPA receptor expression in rats. | Jiang, WN., et al. 2020. Eur J Pharmacol. 884: 173397. PMID: 32717192
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Salinomycin Sodium Salt, 5 mg | sc-208381D | 5 mg | $173.00 | |||
Salinomycin Sodium Salt, 10 mg | sc-208381A | 10 mg | $194.00 | |||
Salinomycin Sodium Salt, 50 mg | sc-208381B | 50 mg | $245.00 | |||
Salinomycin Sodium Salt, 100 mg | sc-208381C | 100 mg | $286.00 | |||
Salinomycin Sodium Salt, 1 g | sc-208381 | 1 g | $439.00 | |||
Salinomycin Sodium Salt, 10 g | sc-208381E | 10 g | $469.00 |