Molecular structure of (S)-TRIP, CAS Number: 874948-63-7
(S)-TRIP (CAS 874948-63-7)
Alternate Names:
(S)-3,3′-Bis(2,4,6-triisopropylphenyl)-1,1′-binaphthyl-2,2′-diyl hydrogenphosphate
Application:
(S)-TRIP is a chiral phosphonic acid
CAS Number:
874948-63-7
Purity:
≥97%
Molecular Weight:
752.96
Molecular Formula:
C50H57O4P
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
(S)-TRIP is a compound that functions as a potent and selective inhibitor of a specific enzyme involved in cellular processes. It acts by binding to the active site of the enzyme, preventing its normal function and disrupting the biochemical pathways in which it participates. This disruption ultimately leads to the inhibition of certain cellular functions, making (S)-TRIP a may be useful for studying the role of the targeted enzyme in various biological processes. By targeting this enzyme, (S)-TRIP can provide insights into the molecular mechanisms underlying cellular functions and contribute to the understanding of related pathways. Its mode of action at the molecular level allows for the investigation of the enzyme′s involvement in cellular signaling, metabolism, or other processes.
(S)-TRIP (CAS 874948-63-7) References
- Organocatalytic asymmetric Povarov reactions with 2- and 3-vinylindoles. | Bergonzini, G., et al. 2010. Chem Commun (Camb). 46: 327-9. PMID: 20024367
- Asymmetric cascade annulation based on enantioselective oxa-Diels-Alder cycloaddition of in situ generated isochromenyliums by cooperative binary catalysis of Pd(OAc)2 and (S)-Trip. | Yu, SY., et al. 2013. J Am Chem Soc. 135: 11402-7. PMID: 23834249
- Gold(I)/chiral Brønsted acid catalyzed enantioselective hydroamination-hydroarylation of alkynes: the effect of a remote hydroxyl group on the reactivity and enantioselectivity. | Shinde, VS., et al. 2015. Chemistry. 21: 975-9. PMID: 25421270
- Asymmetric addition of α-branched cyclic ketones to allenamides catalyzed by a chiral phosphoric acid. | Yang, X. and Toste, FD. 2016. Chem Sci. 7: 2653-2656. PMID: 27990248
- Integration of aerobic oxidation and intramolecular asymmetric aza-Friedel-Crafts reactions with a chiral bifunctional heterogeneous catalyst. | Cheng, HG., et al. 2017. Chem Sci. 8: 1356-1359. PMID: 28451276
- Catalytic Asymmetric Conjugate Addition of Indolizines to α,β-Unsaturated Ketones. | Correia, JTM., et al. 2017. Angew Chem Int Ed Engl. 56: 7967-7970. PMID: 28570759
- Catalytic Asymmetric Mukaiyama-Mannich Reaction of Cyclic C-Acylimines with Difluoroenoxysilanes: Access to Difluoroalkylated Indolin-3-ones. | Li, JS., et al. 2017. Org Lett. 19: 6364-6367. PMID: 29160711
- Enantioselective S-H Insertion Reactions of α-Carbonyl Sulfoxonium Ylides. | Momo, PB., et al. 2020. Angew Chem Int Ed Engl. 59: 15554-15559. PMID: 32352184
- Regio- and Enantioselective Bromocyclization of Difluoroalkenes as a Strategy to Access Tetrasubstituted Difluoromethylene-Containing Stereocenters. | Miller, E., et al. 2020. J Am Chem Soc. 142: 8946-8952. PMID: 32352775
- Modular Design of Chiral Conjugate-Base-Stabilized Carboxylic Acids: Catalytic Enantioselective [4 + 2] Cycloadditions of Acetals. | Zhu, Z., et al. 2020. J Am Chem Soc. 142: 15252-15258. PMID: 32830974
- Catalytic Dynamic Kinetic Resolutions in Tandem to Construct Two-Axis Terphenyl Atropisomers. | Beleh, OM., et al. 2020. J Am Chem Soc. 142: 16461-16470. PMID: 32857500
- Asymmetric Allylation Catalyzed by Chiral Phosphoric Acids: Stereoselective Synthesis of Tertiary Alcohols and a Reagent-Based Switch in Stereopreference. | Lazzarotto, M., et al. 2021. Adv Synth Catal. 363: 3138-3143. PMID: 34413715
- Sterically Demanding Flexible Phosphoric Acids for Constructing Efficient and Multi-Purpose Asymmetric Organocatalysts. | Scharinger, F., et al. 2022. Angew Chem Int Ed Engl. 61: e202202189. PMID: 35413147
- Catalytic enantioselective intramolecular Tishchenko reaction of meso-dialdehyde: synthesis of (S)-cedarmycins. | Ismiyarto, ., et al. 2021. RSC Adv. 11: 11606-11609. PMID: 35423664
- Role of Cinchona Alkaloids in the Enantio- and Diastereoselective Synthesis of Axially Chiral Compounds. | Portolani, C., et al. 2022. Acc Chem Res. 55: 3551-3571. PMID: 36475607
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
(S)-TRIP, 100 mg | sc-236842 | 100 mg | $398.00 |