Date published: 2025-12-30

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(S,S)-(+)-2,6-Bis[2-(hydroxydiphenylmethyl)-1-pyrrolidinyl-methyl]-4-methylphenol

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Alternate Names:
Trost (S,S)-Bis-ProPhenol Ligand; (S,S)-2,6-Bis[2-(hydroxydiphenylmethyl)pyrrolidin-1-ylmethyl]-4-methylphenol
Application:
(S,S)-(+)-2,6-Bis[2-(hydroxydiphenylmethyl)-1-pyrrolidinyl-methyl]-4-methylphenol is A catalyst used in asymmetric aldol, Henry, and Mannich-type reactions
Molecular Weight:
638.84
Molecular Formula:
C43H46N2O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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A catalyst used in asymmetric aldol, Henry, and Mannich-type reactions.


(S,S)-(+)-2,6-Bis[2-(hydroxydiphenylmethyl)-1-pyrrolidinyl-methyl]-4-methylphenol References

  1. Dinuclear asymmetric Zn aldol additions: formal asymmetric synthesis of fostriecin.  |  Trost, BM., et al. 2005. J Am Chem Soc. 127: 3666-7. PMID: 15771479
  2. Group 4 metal complexes of Trost's semi-crown ligand: synthesis, structural characterization and studies on the ring-opening polymerization of lactides and ε-caprolactone.  |  Rajashekhar, B., et al. 2015. Dalton Trans. 44: 16280-93. PMID: 26262508
  3. Enantiomeric impurities in chiral catalysts, auxiliaries, and synthons used in enantioselective syntheses. Part 5.  |  Thakur, N., et al. 2019. Chirality. 31: 688-699. PMID: 31318099
  4. Efficient preparation of (R)-2-(2,5-difluorophenyl)pyrrolidine via a recycle process of resolution.  |  Lv, X., et al. 2021. Chirality. 33: 931-937. PMID: 34651347

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

(S,S)-(+)-2,6-Bis[2-(hydroxydiphenylmethyl)-1-pyrrolidinyl-methyl]-4-methylphenol, 1 g

sc-301724
1 g
$63.00