Date published: 2026-4-25

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S(-)-Raclopride (+)-tartrate salt (CAS 98185-20-7)

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Alternate Names:
3,5-Dichloro-N-(1-ethylpyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxybenzamide (+)-tartrate salt
Application:
CAS Number:
98185-20-7
Purity:
>97%
Molecular Weight:
497.32
Molecular Formula:
C15H20Cl2N2O3·C4H6O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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S(−)-Raclopride (+)-tartrate salt is a D2DR inhibitor.


S(-)-Raclopride (+)-tartrate salt (CAS 98185-20-7) References

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  2. Raclopride-induced motor consolidation impairment in primates: role of the dopamine type-2 receptor in movement chunking into integrated sequences.  |  Levesque, M., et al. 2007. Exp Brain Res. 182: 499-508. PMID: 17653704
  3. In vitro affinities of various halogenated benzamide derivatives as potential radioligands for non-invasive quantification of D(2)-like dopamine receptors.  |  Stark, D., et al. 2007. Bioorg Med Chem. 15: 6819-29. PMID: 17765546
  4. The dopamine agonism on ADP-stimulated platelets is mediated through D2-like but not D1-like dopamine receptors.  |  Schedel, A., et al. 2008. Naunyn Schmiedebergs Arch Pharmacol. 378: 431-9. PMID: 18542926
  5. The Effect of Psychoactive Drugs on in vitro Platelet Function.  |  Schedel, A., et al. 2010. Transfus Med Hemother. 37: 293-298. PMID: 21113253
  6. A highly sensitive LC-MS/MS method for the determination of S-raclopride in rat plasma: application to a pharmacokinetic study in rats.  |  Suresh, PS., et al. 2011. Biomed Chromatogr. 25: 930-7. PMID: 21154642
  7. Effects of dopamine receptor antagonists on the acquisition of ethanol-induced conditioned place preference in mice.  |  Pina, MM. and Cunningham, CL. 2014. Psychopharmacology (Berl). 231: 459-68. PMID: 24005528
  8. Effects of baclofen and raclopride on reinstatement of cocaine self-administration in the rat.  |  Froger-Colléaux, C. and Castagné, V. 2016. Eur J Pharmacol. 777: 147-55. PMID: 26948316
  9. The role of dopamine D1- and D2-like receptors related to muscarinic M1 receptors in impulsive choice in high-impulsive and low-impulsive rats.  |  Tian, L., et al. 2019. Pharmacol Biochem Behav. 176: 43-52. PMID: 30444985
  10. The Appetite Suppressant D-norpseudoephedrine (Cathine) Acts via D1/D2-Like Dopamine Receptors in the Nucleus Accumbens Shell.  |  Kalyanasundar, B., et al. 2020. Front Neurosci. 14: 572328. PMID: 33177980
  11. Combined α2- and D2-receptor blockade activates noradrenergic and dopaminergic neurons, but extracellular dopamine in the prefrontal cortex is determined by uptake and release from noradrenergic terminals.  |  Sagheddu, C., et al. 2023. Front Pharmacol. 14: 1238115. PMID: 37680715
  12. Dopamine receptor antagonist properties of S 14506, 8-OH-DPAT, raclopride and clozapine in rodents.  |  Protais, P., et al. 1994. Eur J Pharmacol. 271: 167-77. PMID: 7698199
  13. Chronic treatment with the D1 receptor antagonist, SCH 23390, and the D2 receptor antagonist, raclopride, in cebus monkeys withdrawn from previous haloperidol treatment. Extrapyramidal syndromes and dopaminergic supersensitivity.  |  Lublin, H., et al. 1993. Psychopharmacology (Berl). 112: 389-97. PMID: 7871047

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

S(-)-Raclopride (+)-tartrate salt, 25 mg

sc-253461
25 mg
$147.00