Molecular structure of (S)-(+)-Apomorphine hydrochloride, CAS Number: 41035-30-7
(S)-(+)-Apomorphine hydrochloride (CAS 41035-30-7)
Alternate Names:
S(+)-APO hydrochloride; S(+)-10,11-Dihydroxyaporphine hydrochloride
Application:
(S)-(+)-Apomorphine hydrochloride is a dopamine receptor antagonist
CAS Number:
41035-30-7
Molecular Weight:
303.78
Molecular Formula:
C17H17NO2•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
(S)-(+)-Apomorphine hydrochloride is a dopamine inhibitor and is inactive as an agonist. It is a powerful emetic used to cure acute poisoning of other chemicals. It finds many applications in research applications. For example, it is employed in models of Parkinson′s disease to study its effects on motor behavior, dopamine function, and neuronal degeneration.
(S)-(+)-Apomorphine hydrochloride (CAS 41035-30-7) References
- An aplysia dopamine1-like receptor: molecular and functional characterization. | Barbas, D., et al. 2006. J Neurochem. 96: 414-27. PMID: 16336222
- Some effects of dopamine transporter and receptor ligands on discriminative stimulus, physiologic, and directly observable indices of opioid withdrawal in rhesus monkeys. | McMahon, LR., et al. 2009. Psychopharmacology (Berl). 203: 411-20. PMID: 18636243
- Dopamine D3 receptors mediate the discriminative stimulus effects of quinpirole in free-feeding rats. | Baladi, MG., et al. 2010. J Pharmacol Exp Ther. 332: 308-15. PMID: 19797621
- Feeding condition and the relative contribution of different dopamine receptor subtypes to the discriminative stimulus effects of cocaine in rats. | Baladi, MG., et al. 2014. Psychopharmacology (Berl). 231: 581-91. PMID: 24030470
- Behavioral effects of apomorphine isomers in the rat: selective locomotor-inhibitory effects of S(+)N-n-propylnorapomorphine. | Campbell, A., et al. 1986. Psychopharmacology (Berl). 88: 158-64. PMID: 3081927
- Metalloaminopeptidases of the Protozoan Parasite Plasmodium falciparum as Targets for the Discovery of Novel Antimalarial Drugs. | Mills, B., et al. 2021. J Med Chem. 64: 1763-1785. PMID: 33534577
- S(+)Apomorphines. Selective inhibition of excitatory effects of dopamine injected into the limbic system of the rat. | Campbell, A., et al. 1985. Neuropharmacology. 24: 391-9. PMID: 4022264
- Stereoisomers of apomorphine differ in affinity and intrinsic activity at presynaptic dopamine receptors modulating [3H]dopamine and [3H]acetylcholine release in slices of cat caudate. | Lehmann, J., et al. 1983. Eur J Pharmacol. 88: 81-8. PMID: 6852106
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
(S)-(+)-Apomorphine hydrochloride, 1 mg | sc-253505D | 1 mg | $280.00 | |||
(S)-(+)-Apomorphine hydrochloride, 5 mg | sc-253505 | 5 mg | $950.00 | |||
(S)-(+)-Apomorphine hydrochloride, 25 mg | sc-253505A | 25 mg | $3400.00 | |||
(S)-(+)-Apomorphine hydrochloride, 50 mg | sc-253505C | 50 mg | $5500.00 | |||
(S)-(+)-Apomorphine hydrochloride, 100 mg | sc-253505B | 100 mg | $10000.00 |