(S)-Norfluoxetine (CAS 126924-38-7)
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(S)-Norfluoxetine, a chiral metabolite of fluoxetine, is notable for its selective inhibition of the serotonin reuptake transporter (SERT), which plays a role in regulating serotonin levels in the synaptic cleft. By selectively binding to SERT, (S)-Norfluoxetine effectively increases the concentration of serotonin, a key neurotransmitter involved in mood regulation, in the synaptic gap, thereby modulating the signaling pathways associated with serotonin. This mechanism underscores its importance in research focused on understanding the complex dynamics of neurotransmitter regulation and the molecular underpinnings of neuropsychiatric disorders. Additionally, the specificity of (S)-Norfluoxetine for the SERT over other neurotransmitter transporters makes it useful in dissecting the roles of serotonin in various physiological and pathological processes, facilitating the development of more targeted and effective strategies for investigating the neural circuitry and molecular biology underlying neurological conditions.
(S)-Norfluoxetine (CAS 126924-38-7) References
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
(S)-Norfluoxetine, 2.5 mg | sc-208373 | 2.5 mg | $316.00 |