S-Nitroso-N-heptanoyl-D,L-penicillamine (CAS 225234-00-4)

S-Nitroso-N-heptanoyl-D,L-penicillamine is a synthetic nitrosothiol compound, structurally characterized by the attachment of a nitric oxide (NO) group to the thiol group of N-heptanoyl-D,L-penicillamine. This modification imparts the compound with the ability to release NO, a reactive nitrogen species that plays a significant role in various biochemical processes. In research, S-Nitroso-N-heptanoyl-D,L-penicillamine is utilized as a nitric oxide donor, enabling the controlled study of NO′s effects in various experimental settings. NO is a key signaling molecule involved in the regulation of vascular tone, immune responses, and neurotransmission, making nitrosothiol compounds like this one invaluable in studies focused on redox biology and cellular signaling. The compound is particularly useful in probing the mechanisms of S-nitrosylation, a post-translational modification of proteins that influences their activity, stability, and interactions. By using S-Nitroso-N-heptanoyl-D,L-penicillamine, researchers can examine the dynamics of NO release and its subsequent interactions with target molecules, facilitating a deeper understanding of NO-mediated pathways. This chemical also serves as a model compound in studies exploring the therapeutic potential of nitrosothiols and their role in modulating oxidative stress and cellular responses to nitrosative stress.