Date published: 2025-10-15

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(S)-MPPG (CAS 201608-25-5)

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Alternate Names:
(S)-α-Methyl-4-phosphonophenylglycine
Application:
(S)-MPPG is a highly potent L-AP4-sensitive receptor antagonist
CAS Number:
201608-25-5
Molecular Weight:
245.17
Molecular Formula:
C9H12NO5P
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

(S)-MPPG is the active isomer of (RS)-MPPG. It is a highly potent L-AP4-sensitive receptor antagonist.


(S)-MPPG (CAS 201608-25-5) References

  1. Asymmetric Strecker-Type Reaction of alpha-Aryl Ketones. Synthesis of (S)-alphaM4CPG, (S)-MPPG, (S)-AIDA, and (S)-APICA, the Antagonists of Metabotropic Glutamate Receptors.  |  Ma, D., et al. 1999. J Org Chem. 64: 120-125. PMID: 11674092
  2. New phenylglycine derivatives with potent and selective antagonist activity at presynaptic glutamate receptors in neonatal rat spinal cord.  |  Jane, DE., et al. 1995. Neuropharmacology. 34: 851-6. PMID: 8532166
  3. Contribution of metabotropic glutamate receptors to the depression of excitatory postsynaptic potentials during hypoxia.  |  de Mendonça, A. and Ribeiro, JA. 1997. Neuroreport. 8: 3667-71. PMID: 9427348
  4. Stereoselective synthesis of (S)-MPPG,(S)-MTPG and (S)-(+)-αM4CPG from (R)-4-hydroxyphenylglycine.  |  Ma, Dawei, and Hongqi Tian. (1997): Journal of the Chemical Society, Perkin Transactions. 1 23: 3493-3496.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

(S)-MPPG, 1 mg

sc-222283
1 mg
$30.00

(S)-MPPG, 5 mg

sc-222283A
5 mg
$96.00