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S-Methyl-L-cysteine (CAS 1187-84-4)

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Alternate Names:
(R)-2-Amino-3-(methylmercapto)propionic acid
Application:
S-Methyl-L-cysteine is a substrate in the catalytic antioxidant system mediated by MSRA
CAS Number:
1187-84-4
Purity:
≥98%
Molecular Weight:
135.18
Molecular Formula:
C4H9NO2S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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S-Methyl-L-cysteine plays a role in the biosynthesis of proteins and is involved in the regulation of cellular processes. S-Methyl-L-cysteine is a sulfur-containing compound with antioxidant properties, which help in protecting cells from damage caused by free radicals. It has the ability to chelate heavy metals, thereby aiding in their excretion.


S-Methyl-L-cysteine (CAS 1187-84-4) References

  1. lcd from Streptococcus anginosus encodes a C-S lyase with alpha,beta-elimination activity that degrades L-cysteine.  |  Yoshida, Y., et al. 2002. Microbiology (Reading). 148: 3961-3970. PMID: 12480900
  2. The formation of S-methyl-L-cysteine sulfoxide from S-methyl-L-cysteine in crucifers.  |  ARNOLD, WN. and THOMPSON, JF. 1962. Biochim Biophys Acta. 57: 604-6. PMID: 13862450
  3. Biosynthesis of s-methyl-L-cysteine and s-methyl-L-cysteine sulfoxide from methionine in garlic.  |  SUGII, M., et al. 1963. Chem Pharm Bull (Tokyo). 11: 135-6. PMID: 13979119
  4. Methionine sulfoxide reductase A and a dietary supplement S-methyl-L-cysteine prevent Parkinson's-like symptoms.  |  Wassef, R., et al. 2007. J Neurosci. 27: 12808-16. PMID: 18032652
  5. Syntheses of metabolites of S-carboxymethyl-L-cysteine and S-methyl-L-cysteine and of some isotopically labelled (2H, 13C) analogues.  |  Meese, CO., et al. 1990. Arch Pharm (Weinheim). 323: 957-65. PMID: 2096798
  6. Increasing effects of S-methyl-L-cysteine on the extracellular D-serine concentrations in the rat medial frontal cortex.  |  Ishiwata, S., et al. 2013. Amino Acids. 44: 1391-5. PMID: 23417484
  7. Study the effect of s-methyl L-cysteine on lipid metabolism in an experimental model of diet induced obesity.  |  G P, S., et al. 2013. J Clin Diagn Res. 7: 2449-51. PMID: 24392369
  8. Pharmacokinetics and N-acetylation metabolism of S-methyl-l-cysteine and trans-S-1-propenyl-l-cysteine in rats and dogs.  |  Amano, H., et al. 2016. Xenobiotica. 46: 1017-25. PMID: 26887651
  9. Evaluation of the Effects of S-Allyl-L-cysteine, S-Methyl-L-cysteine, trans-S-1-Propenyl-L-cysteine, and Their N-Acetylated and S-Oxidized Metabolites on Human CYP Activities.  |  Amano, H., et al. 2016. Biol Pharm Bull. 39: 1701-1707. PMID: 27725449
  10. An LC-MS/MS Method to Measure S-Methyl-l-Cysteine and S-Methyl-l-Cysteine Sulfoxide in Human Specimens Using Isotope Labelled Internal Standards.  |  Sivapalan, T., et al. 2019. Molecules. 24: PMID: 31269651
  11. S-methyl-L-cysteine Protects against Antimycin A-induced Mitochondrial Dysfunction in Neural Cells via Mimicking Endogenous Methionine-centered Redox Cycle.  |  Ni, L., et al. 2020. Curr Med Sci. 40: 422-433. PMID: 32681247
  12. The nutritional role of S-Methyl-L-cysteine.  |  Eyre, MD., et al. 1983. J Sci Food Agric. 34: 696-700. PMID: 6620984
  13. Significance of formate as an intermediate in the oxidation of the methionine, S-methyl-L-cysteine and sarcosine methyl carbons to CO2 in the rat.  |  Case, GL. and Benevenga, NJ. 1977. J Nutr. 107: 1665-76. PMID: 894362
  14. Growth depression and tissue reaction to the consumption of excess dietary methionine and S-methyl-L-cysteine.  |  Benevenga, NJ., et al. 1976. J Nutr. 106: 1714-20. PMID: 993852

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

S-Methyl-L-cysteine, 5 g

sc-258093
5 g
$93.00

S-Methyl-L-cysteine, 25 g

sc-258093A
25 g
$337.00