[S-Methanethiosulfonylcysteaminyl]ethylenediamine-N,N,N′,N′-Tetraacetic Acid (CAS 832733-28-5)

[S-Methanethiosulfonylcysteaminyl]ethylenediamine-N,N,N′,N′-tetraacetic Acid is a complex chelating agent designed for advanced biochemical research, particularly in the study of metal ion interactions within biological systems. This compound integrates the chelating capabilities of ethylenediaminetetraacetic acid (EDTA) with a methanethiosulfonyl group, enhancing its specificity and utility in binding divalent metal ions such as calcium and magnesium. The presence of the methanethiosulfonyl group allows it to form stable thioether bonds with cysteine residues in proteins, providing a unique tool for creating specific and stable modifications in proteins or peptides. The chemical′s application is crucial in understanding the dynamics of metal-protein interactions, especially in enzymes and other proteins where metal ions play a critical role in their biological function. By binding to these ions, the compound can effectively inhibit or modulate enzyme activities, facilitating studies on enzyme mechanisms and the influence of metal cofactors on protein structure and function. Additionally, its ability to attach to specific protein sites makes it valuable in structural biology for mapping out the locations of metal binding and elucidating the structural changes that occur upon metal binding. This specificity and versatility make [S-Methanethiosulfonylcysteaminyl]ethylenediamine-N,N,N′,N′-tetraacetic Acid a potent tool in the fields of enzymology, proteomics, and metalloprotein research, offering detailed insights into the complex interactions that govern cellular metal homeostasis.