Molecular structure of S-Isopropylisothiourea hydrobromide, CAS Number: 57200-31-4
S-Isopropylisothiourea hydrobromide (CAS 57200-31-4)
Application:
S-Isopropylisothiourea hydrobromide is a selective NOS2 inhibitor
CAS Number:
57200-31-4
Molecular Weight:
199.11
Molecular Formula:
C4H10N2S.HBr
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
Technical Information
Safety Information
SDS & Certificate of Analysis
S-Isopropylisothiourea hydrobromide is a potent inhibitor of NOS, with selectivity for NOS2.
S-Isopropylisothiourea hydrobromide (CAS 57200-31-4) References
- Small-molecule screen identifies reactive oxygen species as key regulators of neutrophil chemotaxis. | Hattori, H., et al. 2010. Proc Natl Acad Sci U S A. 107: 3546-51. PMID: 20142487
- Peroxynitrite induces neuronal cell death in aging and age-associated disorders: A review. | Maruyama, W., et al. 2001. J Am Aging Assoc. 24: 11-8. PMID: 23604871
- Potent and selective inhibition of human nitric oxide synthases. Inhibition by non-amino acid isothioureas. | Garvey, EP., et al. 1994. J Biol Chem. 269: 26669-76. PMID: 7523409
- Inhibition of nitric oxide synthase by isothioureas: cardiovascular and antinociceptive effects. | Handy, RL., et al. 1996. Pharmacol Biochem Behav. 55: 179-84. PMID: 8951952
- Selective inhibitors of neuronal nitric oxide synthase--is no NOS really good NOS for the nervous system? | Moore, PK. and Handy, RL. 1997. Trends Pharmacol Sci. 18: 204-11. PMID: 9226999
- Involvement of nitric oxide generation in hypersensitive cell death induced by elicitin in tobacco cell suspension culture | Yamamoto, Ayako, et al. 2004. Journal of General Plant Pathology. 70: 85-92.
Inhibitor of:
NOS2.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
S-Isopropylisothiourea hydrobromide, 10 mg | sc-204252 | 10 mg | $85.00 | |||
S-Isopropylisothiourea hydrobromide, 50 mg | sc-204252A | 50 mg | $359.00 |