Date published: 2025-10-31

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S-Ethyl-L-cysteine (CAS 2629-59-6)

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CAS Number:
2629-59-6
Molecular Weight:
149.21
Molecular Formula:
C5H11NO2S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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S-Ethyl-L-cysteine is a compound of interest in the field of biochemistry, particularly in the study of post-translational modifications of proteins. Researchers utilize this compound to investigate the role of S-alkylation on amino acids in protein structure and function. It serves as a tool in proteomic studies to mimic or probe the effects of natural modifications such as S-ethylation, which can affect protein activity and interactions. In addition, S-Ethyl-L-cysteine is used in the synthesis of peptides and proteins with altered properties, allowing scientists to explore the influence of specific amino acid modifications on biological activity. The compound is also relevant in the analysis of protein folding and stability, providing insights into the dynamic processes that govern protein conformation in living organisms.


S-Ethyl-L-cysteine (CAS 2629-59-6) References

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  2. S-Ethyl-L-cysteine, a member of a new group of antituberculous compounds.  |  SOLOTOROVSKY, M., et al. 1954. Am Rev Tuberc. 70: 806-11. PMID: 13207633
  3. Effect of ventilation on antituberculous activity of S-ethyl-L-cysteine and related compounds.  |  SOLOTOROVSKY, M. 1956. Am Rev Tuberc. 74: 68-71. PMID: 13327216
  4. Effect of DL-ethionine and S-ethyl-L-cysteine on rat liver regeneration.  |  GERSHBEIN, LL. 1958. Am J Physiol. 195: 670-2. PMID: 13606236
  5. Chronometric integrals of product-inhibited enzyme reactions and the hydrolysis of S-ethyl-L-cysteine.  |  SCHWIMMER, S. 1961. Biochim Biophys Acta. 48: 132-8. PMID: 13749272
  6. Ability of S-methyl-L-cysteine to annul the inhibition of yeast growth by L-ethionine and by S-ethyl-L-cysteine.  |  MAW, GA. 1961. J Gen Microbiol. 25: 441-9. PMID: 13768478
  7. The IRC7 gene encodes cysteine desulphydrase activity and confers on yeast the ability to grow on cysteine as a nitrogen source.  |  Santiago, M. and Gardner, RC. 2015. Yeast. 32: 519-32. PMID: 25871637
  8. Sulfoxides, Analogues of L-Methionine and L-Cysteine As Pro-Drugs against Gram-Positive and Gram-Negative Bacteria.  |  Anufrieva, NV., et al. 2015. Acta Naturae. 7: 128-35. PMID: 26798500
  9. Neuroprotective effect of S-allyl-l-cysteine derivatives against endoplasmic reticulum stress-induced cytotoxicity is independent of calpain inhibition.  |  Imai, T., et al. 2016. J Pharmacol Sci. 130: 185-8. PMID: 27032909
  10. Synthesis of S-alkyl-L-cysteine from pyruvate, ammonia and alkyl-mercaptan by cysteine desulfhydrase of Aerobacter aerogenes.  |  Kumagai, H., et al. 1974. Biochem Biophys Res Commun. 59: 789-95. PMID: 4854588
  11. Assay of S-ethyl-N-acetyl-l-cysteine in urine by high-performance liquid chromatography using post-column reaction detection.  |  Eskinja, M., et al. 1997. J Chromatogr B Biomed Sci Appl. 704: 159-65. PMID: 9518145
  12. Pressure and Temperature Effects on the Formation of Aminoacrylate Intermediates of Tyrosine Phenol-lyase Demonstrate Reaction Dynamics  |  Phillips, R. S., Craig, S., Kovalevsky, A., Gerlits, O., Weiss, K., Iorgu, A. I.,.. & Hay, S. 2019. ACS Catalysis. 10(3): 1692-1703.
  13. Target-Based Virtual and Biochemical Screening Against HMG-CoA Reductase Reveals Allium sativum-Derived Organosulfur Compound N-Acetyl Cysteine as a Cardioprotective Agent  |  Ahmad, P., Alvi, S. S., Iqbal, J., & Khan, M. S. 2022. Revista Brasileira de Farmacognosia. 32(6): 962-973.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

S-Ethyl-L-cysteine, 1 g

sc-301716
1 g
$71.00

S-Ethyl-L-cysteine, 5 g

sc-301716A
5 g
$127.00