(S)-CPW 399 CAS: 389888-02-2
MF: C10H13N3O4
MW: 239.23
A subtype-selective weakly desensitising AMPA agonist.

(S)-CPW 399 (CAS 389888-02-2)

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Synonym: (S)-α-Amino-2,3,4,5,6,7-hexahydro-2,4-dioxo-1H-cyclopentapyrimidine-1-propanoic acid
Application: A subtype-selective weakly desensitising AMPA agonist
CAS Number: 389888-02-2
Molecular Weight: 239.23
Molecular Formula: C10H13N3O4
* Refer to Certificate of Analysis for lot specific data (including water content).
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(S)-CPW 399 is a subtype-selective weakly desensitising AMPA agonist. At GluR1 and GluR2 subunit-containing AMPA receptors, exhibits potent agonist activity. Excitotoxic in vitro. AMPA is a transmembrane glutamate receptor composed of the subunits GluR-1,2,3,4.


References

1. Campiani, G., et al. 2001. J. Med. Chem. 44: 4501-4504.
2. Sinclair, C., et al. 2003. Neurochem.Int. 42: 499-510.
3. Butini, S., et al. 2008. J. Med. Chem. 51: 6614-6618.

Physical State :
Solid
Solubility :
Soluble to 50 mM in Water
Storage :
Store at -20° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
657004
SMILES :
C1CC2=C(C1)N(C(=O)NC2=O)C[[email protected]@H](C(=O)O)N

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Certificate of Analysis

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