Date published: 2026-3-12

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(S)-Cotinine N-Oxide (CAS 36508-80-2)

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Alternate Names:
(5S)-1-Methyl-5-(1-oxido-3-pyridinyl)-2-pyrrolidinone
Application:
(S)-Cotinine N-Oxide is a major, carcinogenic metabolite of nicotine in humans
CAS Number:
36508-80-2
Purity:
≥97%
Molecular Weight:
192.21
Molecular Formula:
C10H12N2O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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(S)-Cotinine N-oxide has become a subject of interest in analytical chemistry for its use as a biomarker in the assessment of environmental tobacco smoke exposure. In research focused on nicotine metabolism, this compound is pivotal due to its stability, which facilitates the study of nicotine′s metabolic pathways and its metabolites′ mechanisms. The compound′s unique properties also enable researchers to use it as a standard in the development of sensitive and specific detection methods such as liquid chromatography-mass spectrometry. In toxicological studies, (S)-Cotinine N-oxide is employed to understand the impact of oxidative stress on the metabolism of nicotine-related compounds. Its role in the quantification of second-hand smoke exposure is also critical in environmental health studies, aiding in the establishment of exposure-risk relationships.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

(S)-Cotinine N-Oxide, 25 mg

sc-212882
25 mg
$426.00