Molecular structure of (S)-Citalopram Oxalate, CAS Number: 219861-08-2
(S)-Citalopram Oxalate (CAS 219861-08-2)
See product citations (3)
Alternate Names:
Escitalopram Oxalate
Application:
(S)-Citalopram Oxalate is a potential serotonin (5-HT) uptake inhibitor
CAS Number:
219861-08-2
Purity:
≥98%
Molecular Weight:
414.43
Molecular Formula:
C22H23FN2O5
Supplemental Information:
This is as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
(S)-Citalopram Oxalate is a derivative of Citalopram (sc-201123). Citalopram is a selective inhibitor of the ST (5-hydroxytryptamine transporter, serotonin) and therefore is a potent and selective serotonin reuptake inhibitor. Additional studies in indicate that Citalopram may be a weak, allosteric modulator of serotonin in a cross-species chimeric study. Studies also indicate that Citalopram is useful for studying gene expression patterns in circulating lymphocytes. In zebrafish, Citalopram is noted to reduce the frequency of NMDA-induced locomotor rhythm involved in swimming behavor.
(S)-Citalopram Oxalate (CAS 219861-08-2) References
- Plasma membrane monoamine transporters: structure, regulation and function. | Torres, GE., et al. 2003. Nat Rev Neurosci. 4: 13-25. PMID: 12511858
- The effect of citalopram on gene expression profile of Alzheimer lymphocytes. | Palotás, A., et al. 2004. Neurochem Res. 29: 1563-70. PMID: 15260135
- Dissection of an allosteric mechanism on the serotonin transporter: a cross-species study. | Neubauer, HA., et al. 2006. Mol Pharmacol. 69: 1242-50. PMID: 16434615
- Serotonergic modulation of locomotion in zebrafish: endogenous release and synaptic mechanisms. | Gabriel, JP., et al. 2009. J Neurosci. 29: 10387-95. PMID: 19692613
- A highly sensitive LC-MS/MS method for the determination of S-citalopram in rat plasma: application to a pharmacokinetic study in rats. | Suresh, PS., et al. 2010. Biomed Chromatogr. 24: 1052-8. PMID: 20352615
- Effects of diverse psychopharmacological substances on the activity of brain prolyl oligopeptidase. | Peltonen, I. and Männistö, PT. 2011. Basic Clin Pharmacol Toxicol. 108: 46-54. PMID: 20825390
- Formation of solid solutions between racemic and enantiomeric citalopram oxalate. | de Diego, HL., et al. 2011. Chirality. 23: 408-16. PMID: 21472783
- Perinatal vs genetic programming of serotonin states associated with anxiety. | Altieri, SC., et al. 2015. Neuropsychopharmacology. 40: 1456-70. PMID: 25523893
- Enantiomeric impurity analysis using circular dichroism spectroscopy with United States Pharmacopeia liquid chromatographic methods. | Kirkpatrick, D., et al. 2018. J Pharm Biomed Anal. 156: 366-371. PMID: 29754067
- Direct visualization of an antidepressant analog using surface-enhanced Raman scattering in the brain. | Tanuma, M., et al. 2020. JCI Insight. 5: PMID: 32125287
- Cross-validated Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging Quantitation Protocol for a Pharmaceutical Drug and Its Drug-Target Effects in the Brain Using Time-of-Flight and Fourier Transform Ion Cyclotron Resonance Analyzers. | Källback, P., et al. 2020. Anal Chem. 92: 14676-14684. PMID: 33086792
- Unravelling the antimicrobial action of antidepressants on gut commensal microbes. | Ait Chait, Y., et al. 2020. Sci Rep. 10: 17878. PMID: 33087796
- Evidence of the Dysbiotic Effect of Psychotropics on Gut Microbiota and Capacity of Probiotics to Alleviate Related Dysbiosis in a Model of the Human Colon. | Ait Chait, Y., et al. 2023. Int J Mol Sci. 24: PMID: 37108487
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
(S)-Citalopram Oxalate, 10 mg | sc-208365 | 10 mg | $250.00 | |||
(S)-Citalopram Oxalate, 100 mg | sc-208365A | 100 mg | $680.00 |