Date published: 2026-2-5

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S-Carboxymethyl-L-cysteine (CAS 638-23-3)

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Alternate Names:
carbocistein; Carbocisteine; S-(Carboxymethyl)-(R)-cysteine
Application:
S-Carboxymethyl-L-cysteine is a mucolytic agent
CAS Number:
638-23-3
Purity:
98%
Molecular Weight:
179.195
Molecular Formula:
C5H9NO4S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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S-Carboxymethyl-L-cysteine is a compound that functions as a mucolytic agent in experimental applications. It acts by breaking disulfide bonds in mucoproteins, reducing the viscosity of mucus. S-Carboxymethyl-L-cysteinel′s mode of action involves disrupting the structure of mucus, leading to a decrease in its thickness and making it easier to clear from the airways. S-Carboxymethyl-L-cysteine achieves this by cleaving the disulfide bonds within the mucus, resulting in a reduction in its elasticity and adhesiveness. S-Carboxymethyl-L-cysteine′s mechanism of action may involve altering the physical properties of mucus


S-Carboxymethyl-L-cysteine (CAS 638-23-3) References

  1. The sulphoxidation of S-carboxymethyl-L-cysteine in COPD.  |  Steventon, GB. and Mitchell, SC. 2006. Eur Respir J. 27: 865-6. PMID: 16585098
  2. The pharmacokinetics of orally administered S-carboxymethyl-L-cysteine in the dog, calf and sheep.  |  Panagopoulos, P., et al. 2010. Eur J Pharm Sci. 39: 219-23. PMID: 20035864
  3. An investigation into possible xenobiotic-endobiotic inter-relationships involving the amino acid analogue drug, S-carboxymethyl-L-cysteine and plasma amino acids in humans.  |  Steventon, GB., et al. 2012. Amino Acids. 42: 1967-73. PMID: 21559953
  4. S-carboxymethyl-L-cysteine.  |  Mitchell, SC. and Steventon, GB. 2012. Drug Metab Rev. 44: 129-47. PMID: 22497630
  5. S-carboxymethyl-L-cysteine and it (R/S)-S-oxides in beagle dog plasma and hepatic cytosol.  |  Panagopoulos, P., et al. 2015. Xenobiotica. 45: 1047-53. PMID: 26068525
  6. Phenylalanine monooxygenase and the sulfur oxygenation of S-carboxymethyl-L-cysteine in mice.  |  Vandenbossche, E., et al. 2016. Xenobiotica. 46: 379-84. PMID: 26338263
  7. The deficiency of sulfoxidation of S-carboxymethyl-L-cysteine.  |  Mitchell, SC. and Waring, RH. 1989. Pharmacol Ther. 43: 237-49. PMID: 2675135
  8. The S-oxidation of S-carboxymethyl-L-cysteine in hepatic cytosolic fractions from BTBR and phenylketonuria enu1 and enu2 mice.  |  Steventon, GB. and Mitchell, SC. 2019. Xenobiotica. 49: 495-502. PMID: 29648495
  9. Comparison of the sulfur-oxygenation of cysteine and S-carboxymethyl-l-cysteine in human hepatic cytosol and the rôle of cysteine dioxygenase.  |  Steventon, GB., et al. 2018. J Pharm Pharmacol. 70: 1069-1077. PMID: 29882598
  10. Pharmacogenetics of the S-oxidation of S-carboxymethyl-L-cysteine.  |  Waring, RH. 1988. Drug Metabol Drug Interact. 6: 253-63. PMID: 3078290
  11. S-Carboxymethyl-L-cysteine-induced Fixed Drug Eruption.  |  Fukuda, H. and Takahashi, M. 2019. Acta Derm Venereol. 99: 689-690. PMID: 30938829
  12. Structure, Antioxidant and Anti-inflammatory Activities of the (4R)- and (4S)-epimers of S-Carboxymethyl-L-cysteine Sulfoxide.  |  Waters, JK., et al. 2020. Pharmaceuticals (Basel). 13: PMID: 32992738
  13. S-Carboxymethyl-l-cysteine: a multiple dosing study using pharmacokinetic modelling.  |  Steventon, GB. and Mitchell, SC. 2021. Xenobiotica. 51: 865-870. PMID: 33974496
  14. S-Carboxymethyl Cysteine Protects against Oxidative Stress and Mitochondrial Impairment in a Parkinson's Disease In Vitro Model.  |  Catanesi, M., et al. 2021. Biomedicines. 9: PMID: 34680584

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

S-Carboxymethyl-L-cysteine, 25 g

sc-272300
25 g
$64.00