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S-β-(4-Pyridylethyl)-L-cysteine (CAS 28809-04-3)

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Alternate Names:
PEC; 2-AMINO-3-(2-PYRIDIN-4-YL-ETHYLSULFANYL)-PROPIONIC ACID
CAS Number:
28809-04-3
Molecular Weight:
226.30
Molecular Formula:
C10H14N2O2S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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S-beta-(4-Pyridylethyl)-L-cysteine is a specialized derivative of the amino acid L-cysteine, characterized by the substitution of its hydrogen atom with a 4-pyridylethyl group at the beta position of the cysteine molecule. This modification introduces a pyridine ring, a nitrogen-containing heterocycle, linked through an ethyl chain to the thiol group of cysteine, thereby enhancing the molecule′s chemical properties and reactivity. The presence of the pyridine moiety confers unique electronic and structural characteristics to the compound, facilitating its interaction with various chemical and biological entities. This compound finds extensive application in the realm of biochemical and pharmacological research, particularly in studies aimed at understanding protein structure and function, enzyme mechanisms, and the intricate processes of cellular signaling and regulation.


S-β-(4-Pyridylethyl)-L-cysteine (CAS 28809-04-3) References

  1. Development of an amino acid sequence and D/L-configuration determination method of peptide with a new fluorescence Edman reagent, 7-methylthio-4-(2,1,3-benzoxadiazolyl) isothiocyanate.  |  Toriba, A., et al. 2000. Anal Chem. 72: 732-9. PMID: 10701257
  2. Cycloviolins A-D, anti-HIV macrocyclic peptides from Leonia cymosa.  |  Hallock, YF., et al. 2000. J Org Chem. 65: 124-8. PMID: 10813905
  3. Plasma protein pentosidine and carboxymethyllysine, biomarkers for age-related macular degeneration.  |  Ni, J., et al. 2009. Mol Cell Proteomics. 8: 1921-33. PMID: 19435712
  4. Some optical properties of S- -(4-pyridylethyl)-L-cysteine and its wheat gluten and serum albumin derivatives.  |  Wu, YV., et al. 1971. Can J Biochem. 49: 1042-9. PMID: 5168481
  5. An internal standard for amino acid analyses: S-beta-(4-pyridylethyl)-L-cysteine.  |  Cavins, JF. and Friedman, M. 1970. Anal Biochem. 35: 489-93. PMID: 5385058
  6. Biochemical studies on the toxicity of 1, 1'-dimethyl-4, 4'-bipyridylium dichloride in the rat.  |  Nwabisi, VC. and Nwanze, EA. 1997. Comp Biochem Physiol C Pharmacol Toxicol Endocrinol. 117: 103-9. PMID: 9185332

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

S-β-(4-Pyridylethyl)-L-cysteine, 1 g

sc-296294
1 g
$204.00