Molecular structure of S-Benzyl-L-cysteine p-nitroanilide, CAS Number: 7436-62-6
S-Benzyl-L-cysteine p-nitroanilide (CAS 7436-62-6)
Alternate Names:
L-Cys(Bzl)-pNA
Application:
S-Benzyl-L-cysteine p-nitroanilide is a substrate used for the assay of oxytocinase (IRAP)
CAS Number:
7436-62-6
Purity:
≥97%
Molecular Weight:
331.43
Molecular Formula:
C16H17N3O3S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
S-Benzyl-L-cysteine p--nitroanilide is a substrate used for the assay of IRAP (oxytocinase). IRAP (Insulin-responsive aminopeptidase), also known as LNPEP (Leucyl-cystinyl aminopeptidase), OTase (Oxytocinase) or P-LAP (Placental leucine aminopeptidase), is a 1,025 amino acid protein that is highly expressed in placenta, heart, kidney and small intestine and at lower levels in neuronal cells in brain, in skeletal muscle, spleen, liver, testis and colon.
S-Benzyl-L-cysteine p-nitroanilide (CAS 7436-62-6) References
- A rapid and specific method for the determination of oxytocinase (cystine aminopeptidase) activity using continuous flow analysis and S-benzyl-L-cysteine-p-nitroanilide as substrate. | Small, CW. and Watkins, WB. 1975. Clin Biochem. 8: 124-32. PMID: 1168550
- Oxytocinase activity in human spermatozoa and its possible role in fertilization. | Roy, AC. and Ratnam, SS. 1990. Arch Androl. 25: 1-4. PMID: 2389986
- Vasopressinase Activity: A Potential Early Biomarker for Detecting Cardiopulmonary Bypass-Associated Acute Kidney Injury? | Kim, N., et al. 2016. Thorac Cardiovasc Surg. 64: 555-560. PMID: 26366890
- Prostaglandins, not cyclic GMP, inhibit oxytocinase isoenzymes from human amniotic fluid in vitro. | Roy, AC., et al. 1985. Prostaglandins. 30: 255-61. PMID: 2996058
- Inhibition of serum oxytocinase activity by prostaglandins. | Roy, AC., et al. 1981. Prostaglandins Med. 6: 577-87. PMID: 6267639
- pH dependent inhibition of serum oxytocinase activity by prostaglandins and cyclic GMP. | Roy, AC., et al. 1982. Prostaglandins Leukot Med. 8: 173-9. PMID: 6281812
- Selective inhibition of multimolecular forms of human serum and placental oxytocinase activity by prostaglandins and cyclic GMP. | Roy, AC., et al. 1984. Prostaglandins Leukot Med. 14: 105-11. PMID: 6328538
- Cystyl aminopeptidase in maternal serum for the antenatal recognition of fetal growth retardation. | Gopalaswamy, G., et al. 1983. Aust N Z J Obstet Gynaecol. 23: 79-84. PMID: 6578781
- The use of human placental lactogen, oxytocinase and estriol in twin pregnancies with intrauterine growth retardation. | Briët, JW. and Hoorn, RK. 1982. Eur J Obstet Gynecol Reprod Biol. 13: 7-14. PMID: 7060818
- Comparison of substrates for measuring cystyl-amino peptidase activity in serum of pregnancy and hepatic disease and in various tissues. | Uete, T., et al. 1981. J Clin Chem Clin Biochem. 19: 145-54. PMID: 7229578
- Cystine aminopeptidases from pregnancy serum and placenta. | Hiwada, K., et al. 1978. Biochem Med. 20: 296-304. PMID: 752337
- An aminopeptidase activity from porcine kidney that hydrolyzes oxytocin and vasopressin: purification and partial characterization. | Itoh, C. and Nagamatsu, A. 1995. Biochim Biophys Acta. 1243: 203-8. PMID: 7873563
- Decreased levels of amniotic fluid oxytocinase activity in preeclampsia. | Roy, AC., et al. 1993. Gynecol Obstet Invest. 35: 166-8. PMID: 8505009
Substrate of:
Enzyme, and IRAP.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
S-Benzyl-L-cysteine p-nitroanilide, 250 mg | sc-253447 | 250 mg | $90.00 |