![(S)-α,α-Bis[3,5-bis(trifluoromethyl)phenyl]-2-pyrrolidinemethanol (CAS 848821-76-1) - chemical structure image](https://media.scbt.com/product/s-alpha-alpha-bis3-5-bistrifluoromethylphenyl-2-pyrrolidinemethanol-848821-76-1-structure_17_45_b_174587.jpg)
![(S)-α,α-Bis[3,5-bis(trifluoromethyl)phenyl]-2-pyrrolidinemethanol (CAS 848821-76-1) - chemical structure image](https://media.scbt.com/product/s-alpha-alpha-bis3-5-bistrifluoromethylphenyl-2-pyrrolidinemethanol-848821-76-1-structure_17_45_t_174587.jpg "Molecular structure of (S)-α,α-Bis[3,5-bis(trifluoromethyl)phenyl]-2-pyrrolidinemethanol, CAS Number: 848821-76-1")
Molecular structure of (S)-α,α-Bis[3,5-bis(trifluoromethyl)phenyl]-2-pyrrolidinemethanol, CAS Number: 848821-76-1
(S)-α,α-Bis[3,5-bis(trifluoromethyl)phenyl]-2-pyrrolidinemethanol (CAS 848821-76-1)
Alternate Names:
(S)-2-{Bis[3,5-bis(trifluoromethyl)phenyl]hydroxymethyl}pyrrolidine
CAS Number:
848821-76-1
Purity:
≥99%
Molecular Weight:
525.33
Molecular Formula:
C21H15F12NO
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
(S)-α,α-Bis[3,5-bis(trifluoromethyl)phenyl]-2-pyrrolidinemethanol is a chiral ligand, used in catalytic asymmetric synthesis. Its application extends to the production of propargylic sulfamidates and cyclic imines. It has shown to have a high yield in enantioselective reactions with terminal alkynes. (S)-α,α-Bis[3,5-bis(trifluoromethyl)phenyl]-2-pyrrolidinemethanol has been studied for its ability to act as a catalyst in diverse reactions and its engagement as a reactant in various chemical reactions.
(S)-α,α-Bis[3,5-bis(trifluoromethyl)phenyl]-2-pyrrolidinemethanol (CAS 848821-76-1) References
- Retention of fluorinated chiral selectors in biphasic fluorinated solvent systems and its application to the separation of enantiomers by countercurrent chromatography. | Pérez, AM. and Minguillón, C. 2010. J Chromatogr A. 1217: 1094-100. PMID: 19833342
- Cooperative catalytic reactions using organocatalysts and transition-metal catalysts: enantioselective propargylic alkylation of propargylic alcohols with aldehydes. | Ikeda, M., et al. 2010. Angew Chem Int Ed Engl. 49: 7289-93. PMID: 20629065
- Catalytic Enantioselective Aza-Reformatsky Reaction with Cyclic Imines. | De Munck, L., et al. 2016. Chemistry. 22: 17590-17594. PMID: 27775191
- Diarylprolinol as an Effective Organocatalyst in Asymmetric Cross-aldol Reactions of Two Different Aldehydes. | Hayashi, Y. 2022. Chem Rec. e202200159. PMID: 35896950
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| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
(S)-α,α-Bis[3,5-bis(trifluoromethyl)phenyl]-2-pyrrolidinemethanol, 1 g | sc-236825 | 1 g | $89.00 |