Molecular structure of (S)-3-Hydroxyphenylglycine, CAS Number: 71301-82-1
(S)-3-Hydroxyphenylglycine (CAS 71301-82-1)
Alternate Names:
(S)-3H-PG
Application:
(S)-3-Hydroxyphenylglycine is an agonist at group I metabotrobic glutamate receptors
CAS Number:
71301-82-1
Purity:
≥99%
Molecular Weight:
167.16
Molecular Formula:
C8H9NO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Available in US only.
Available in US only.
* Refer to Certificate of Analysis for lot specific data.
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Description
Technical Information
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SDS & Certificate of Analysis
(S)-3-Hydroxyphenylglycine is an agonist at group I metabotropic glutamate receptors (mGluR) having no effect at mGluR-2 or mGluR-4.
(S)-3-Hydroxyphenylglycine (CAS 71301-82-1) References
- Group I mGluR activation turns on a voltage-gated inward current in hippocampal pyramidal cells. | Chuang, SC., et al. 2000. J Neurophysiol. 83: 2844-53. PMID: 10805682
- Characterization of [(3)H]Quisqualate binding to recombinant rat metabotropic glutamate 1a and 5a receptors and to rat and human brain sections. | Mutel, V., et al. 2000. J Neurochem. 75: 2590-601. PMID: 11080213
- The activation of metabotropic glutamate receptors differentially affects GABA and alpha-melanocyte stimulating hormone release from the hypothalamus and the posterior pituitary of male rats. | Pampillo, M., et al. 2002. Neurosci Lett. 327: 95-8. PMID: 12098644
- Phenylglycine derivatives as new pharmacological tools for investigating the role of metabotropic glutamate receptors in the central nervous system. | Birse, EF., et al. 1993. Neuroscience. 52: 481-8. PMID: 7680790
- Metabotropic glutamate group II receptors are responsible for the depression of synaptic transmission induced by ACPD in the dentate gyrus. | Ugolini, A. and Bordi, F. 1995. Eur J Pharmacol. 294: 403-10. PMID: 8750700
- Metabotropic glutamate receptors coupled to IP3 production mediate inhibition of IAHP in rat dentate granule neurons. | Abdul-Ghani, MA., et al. 1996. J Neurophysiol. 76: 2691-700. PMID: 8899638
- Membrane-delimited modulation of NMDA currents by metabotropic glutamate receptor subtypes 1/5 in cultured mouse cortical neurons. | Yu, SP., et al. 1997. J Physiol. 499 (Pt 3): 721-32. PMID: 9130168
- Metabotropic glutamate receptor subtypes mediating slow inward tail current (IADP) induction and inhibition of synaptic transmission in olfactory cortical neurones. | Libri, V., et al. 1997. Br J Pharmacol. 120: 1083-95. PMID: 9134221
- Role of group I metabotropic glutamate receptors in the patterning of epileptiform activities in vitro. | Merlin, LR. and Wong, RK. 1997. J Neurophysiol. 78: 539-44. PMID: 9242303
- Involvement of a cyclic-AMP pathway in group I metabotropic glutamate receptor responses in neonatal rat cortex. | Schaffhauser, H., et al. 1997. Eur J Pharmacol. 334: 289-97. PMID: 9369360
- Metabotropic glutamate receptors are involved in long-term potentiation in isolated slices of rat medial frontal cortex. | Vickery, RM., et al. 1997. J Neurophysiol. 78: 3039-46. PMID: 9405523
- Characterization of an intracellular alkaline shift in rat astrocytes triggered by metabotropic glutamate receptors. | Amos, BJ. and Chesler, M. 1998. J Neurophysiol. 79: 695-703. PMID: 9463433
- Activation of group I metabotropic glutamate receptors elicits pH changes in cultured rat cortical glia and neurons. | Amos, BJ., et al. 1998. Neuroscience. 86: 1109-20. PMID: 9697118
Activator of:
mGluR-1a, and mGluR-1b.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
(S)-3-Hydroxyphenylglycine, 10 mg | sc-204254 | 10 mg | $225.00 | |||
| US: Only available in the US | ||||||
(S)-3-Hydroxyphenylglycine, 50 mg | sc-204254A | 50 mg | $930.00 | |||
| US: Only available in the US | ||||||