Date published: 2026-4-29

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(S)-3-Hydroxy-2-methyl-propionic acid (CAS 26543-05-5)

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Alternate Names:
Propanoic acid, 3-hydroxy-2-methyl-, (2S)-; (S)-3-Hydroxy-2-methylpropanoic acid
CAS Number:
26543-05-5
Purity:
≥95%
Molecular Weight:
104.10
Molecular Formula:
C4H8O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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(S)-3-Hydroxy-2-methyl-propionic acid, a compound derived from the breakdown of leucine, an essential amino acid, is present in certain food sources. This molecule exhibits chirality, existing as two mirror-image forms. Its utilization extends to the exploration of enzymes involved in leucine metabolism. (S)-3-Hydroxy-2-methyl-propionic acid has served as useful in investigating the impact of leucine on protein synthesis, energy metabolism, and the intricate processes underlying muscle growth and development.


(S)-3-Hydroxy-2-methyl-propionic acid (CAS 26543-05-5) References

  1. Total synthesis of bafilomycin A(1) relying on iterative 1,2-induction in acyclic precursors.  |  Hanessian, S., et al. 2001. J Am Chem Soc. 123: 10200-6. PMID: 11603969
  2. Strategy and methodology development for the total synthesis of polyether ionophore antibiotics.  |  Faul, MM. and Huff, BE. 2000. Chem Rev. 100: 2407-74. PMID: 11749289
  3. Optical isomers of 3,13-dimethylheptadecane: Sex pheromone components of the western false hemlock looper,Nepytia freemani (Lepidoptera: Geometridae).  |  Skip King, GG., et al. 1995. J Chem Ecol. 21: 2027-45. PMID: 24233904
  4. A General Solution to the Modular Synthesis of Polyketide Building Blocks by Kanemasa Hydroxy-Directed Nitrile Oxide Cycloadditions.  |  Bode, JW., et al. 2001. Angew Chem Int Ed Engl. 40: 2082-2085. PMID: 29712193
  5. Large-Scale Synthesis of the Anti-Cancer Marine Natural Product (+)-Discodermolide. Part 1:  Synthetic Strategy and Preparation of a Common Precursor  |  Stuart J. Mickel, Gottfried H. Sedelmeier, Daniel Niederer, Robert Daeffler, Adnan Osmani, Klaus Schreiner, Manuela Seeger-Weibel, Brigitte Bérod, Karl Schaer, Remo Gamboni, Stephen Chen, Weichun Chen, Christopher T. Jagoe, Frederick R. Kinder, Mauricio Loo, Kapa Prasad, Oljan Repič, Wen-Chung Shieh, Run-Ming Wang, Liladhar Waykole, David D. Xu, and Song Xue. 2004,. Org. Proc. Res. Dev. 8, 1,: 92–100.
  6. Synthesis of Hydroxy Group-Containing Poly(N-Propargylamides): Examination of the Secondary Structure and Chiral-Recognition Ability of the Polymers  |   and Fumio Sanda, Toru Fujii, Junichi Tabei, Masashi Shiotsuki, Toshio Masuda. Pages 112-118. Macromolecular Chemistry and Physics. Volume209, Issue1: Pages 112-118.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

(S)-3-Hydroxy-2-methyl-propionic acid, 10 mg

sc-272408
10 mg
$125.00