MF: C9H9NO5 MW: 211.17 A mixed group II mGlu agonist and group I metabotropic glutamate receptor antagonist.
Protein-Interacting Inhibitors, Activators & Substrates
(S)-3-Carboxy-4-hydroxyphenylglycine (CAS 55136-48-6)
C 9H 9NO 5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. *
Certificate of Analysis for lot specific data (including water content).
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(S)-3-Carboxy-4-hydroxyphenylglycine is a mixed group II mGluR agonist and group I metabotropic glutamate receptor antagonist.
1. Hayashi, Y., et al. 1994. J. Neurosci. 14: 3370-3377.
2. Watkins, J. and Collingridge, G 1994. Trends Pharmacol Sci. 15: 333-342. 3. Sekiyama, N., et al. 1996. Br. J. Pharmacol. 117: 1493-1503.
Soluble in water (25 mM), dilute aqueous base, and 1 eq. NaOH (100 mM).
Store at room temperature
300.40° C (Predicted)
~466.4° C at 760 mmHg (Predicted)
20 D 1.68 (Predicted)
α20/D +133.3°, c = 0.75 in 6N HCl
50 = 40 µM (human)
a: 2.03 (Predicted), pK b: 10.4 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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