Date published: 2025-12-25

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(S)-(−)-3,3,3-Trifluoro-1,2-epoxypropane (CAS 130025-34-2)

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Alternate Names:
(S)-(−)-2-(Trifluoromethyl)oxirane
CAS Number:
130025-34-2
Purity:
≥97%
Molecular Weight:
112.05
Molecular Formula:
C3H3F3O
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Precursor to a trifluoromethyl chiral auxiliary which promotes a highly diastereoselective Simmons-Smith cyclopropanation. (S)-(−)-3,3,3-Trifluoro-1,2-epoxypropane is an enantiomerically pure oxirane compound with chirality. Its application in chemical synthesis includes its use as a protective group, enabling precise control over the reactivity of molecules. In the field of material science, it finds utility in the preparation of optically active polymers, contributing to the development of materials with desired optical properties.


(S)-(−)-3,3,3-Trifluoro-1,2-epoxypropane (CAS 130025-34-2) References

  1. Trifluoromethylated amino alcohol as chiral auxiliary for highly diastereoselective and fast Simmons–Smith cyclopropanation of allylic amine  |  T Katagiri, N Iguchi, T Kawate, S Takahashi… - Tetrahedron …,. 18 April 2006. Tetrahedron: Asymmetry. Volume 17, Issue 8,,: Pages 1157-1160.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

(S)-(−)-3,3,3-Trifluoro-1,2-epoxypropane, 250 mg

sc-258106
250 mg
$155.00

(S)-(−)-3,3,3-Trifluoro-1,2-epoxypropane, 1 g

sc-258106A
1 g
$480.00