S-100A16 Antibody (G-7): sc-390151
- S-100A16 Antibody (G-7) is a mouse monoclonal IgG1 κ S-100A16 antibody provided at 200 µg/ml
- raised against amino acids 1-103 representing full length S-100A16 of human origin
- S-100A16 Antibody (G-7) is recommended for detection of S-100A16 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-S-100A16 Antibody (G-7) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP is the preferred secondary detection reagent for S-100A16 Antibody (G-7) for WB and IHC(P) applications. This reagent is now offered in a bundle with S-100A16 Antibody (G-7) (see ordering information below).
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S-100A16 Antibody (G-7) is a mouse monoclonal IgG1 kappa light chain antibody that detects S-100A16 of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). S-100A16 (G-7) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. S-100A16, also known as AAG13 or S100 calcium binding protein A16, is a 103 amino acid protein that plays a crucial role in cellular processes, particularly in calcium signaling pathway regulation. S-100A16 is primarily located in the nucleus and cytoplasm, where S-100A16 exists as a homodimer, binding one calcium ion per monomer. Two EF-hand domains within S-100A16′s structure allow conformational changes upon calcium binding, which is essential for modulating various cellular activities, including cell growth, differentiation, and stress response. S-100A16 expression is particularly relevant in pathological conditions, as S-100A16 is involved in inflammatory responses and may influence tumor cell motility, making S-100A16 a significant marker for studying cancer and neurodegenerative diseases. Encoded by a gene located on human chromosome 1q21.3, S-100A16′s diverse roles in cellular signaling underscore S-100A16′s importance in both normal physiology and disease states, highlighting anti-S-100A16 antibody (G-7)′s utility in research applications.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
S-100A16 Antibody (G-7) References:
- Functional roles of S100 proteins, calcium-binding proteins of the EF-hand type. | Donato, R. 1999. Biochim Biophys Acta. 1450: 191-231. PMID: 10395934
- Molecular mechanisms of S100-target protein interactions. | Zimmer, DB., et al. 2003. Microsc Res Tech. 60: 552-9. PMID: 12645003
- S100A16, a ubiquitously expressed EF-hand protein which is up-regulated in tumors. | Marenholz, I. and Heizmann, CW. 2004. Biochem Biophys Res Commun. 313: 237-44. PMID: 14684152
- S100 proteins in mouse and man: from evolution to function and pathology (including an update of the nomenclature). | Marenholz, I., et al. 2004. Biochem Biophys Res Commun. 322: 1111-22. PMID: 15336958
- Calcium-dependent and -independent interactions of the S100 protein family. | Santamaria-Kisiel, L., et al. 2006. Biochem J. 396: 201-14. PMID: 16683912
- S100A16, a novel calcium-binding protein of the EF-hand superfamily. | Sturchler, E., et al. 2006. J Biol Chem. 281: 38905-17. PMID: 17030513
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
S-100A16 Antibody (G-7) | sc-390151 | 200 µg/ml | $322.00 | |||
S-100A16 Antibody (G-7): m-IgG Fc BP-HRP Bundle | sc-526128 | 200 µg Ab; 10 µg BP | $361.00 | |||
S-100A16 Antibody (G-7) AC | sc-390151 AC | 500 µg/ml, 25% agarose | $424.00 | |||
S-100A16 Antibody (G-7) HRP | sc-390151 HRP | 200 µg/ml | $322.00 | |||
S-100A16 Antibody (G-7) FITC | sc-390151 FITC | 200 µg/ml | $336.00 | |||
S-100A16 Antibody (G-7) PE | sc-390151 PE | 200 µg/ml | $349.00 | |||
S-100A16 Antibody (G-7) Alexa Fluor® 488 | sc-390151 AF488 | 200 µg/ml | $364.00 | |||
S-100A16 Antibody (G-7) Alexa Fluor® 546 | sc-390151 AF546 | 200 µg/ml | $364.00 | |||
S-100A16 Antibody (G-7) Alexa Fluor® 594 | sc-390151 AF594 | 200 µg/ml | $364.00 | |||
S-100A16 Antibody (G-7) Alexa Fluor® 647 | sc-390151 AF647 | 200 µg/ml | $364.00 | |||
S-100A16 Antibody (G-7) Alexa Fluor® 680 | sc-390151 AF680 | 200 µg/ml | $364.00 | |||
S-100A16 Antibody (G-7) Alexa Fluor® 790 | sc-390151 AF790 | 200 µg/ml | $364.00 |