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S-100 α chain Antibody (4c4.9) is a mouse monoclonal IgG2a antibody that detects the S-100 α chain protein of mouse, rat, and human by applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). S-100 α chain is a member of the S-100 protein family, which plays a crucial role in regulating various cellular processes, including cell cycle progression and differentiation. S-100 α chain protein activates calcium-induced calcium release, thereby influencing muscle contraction and neurotransmitter release. S-100 α chain protein forms dimers with S-100 β chain, and these complexes are essential for mediating biological functions. S-100 α chain protein is predominantly localized in the cytoplasm and nuclei of astrocytes, Schwann cells, and certain tumors, highlighting significance in both normal physiology and pathological conditions. S-100 α chain protein presence in various tissues, including the brain and skin, underscores potential as a biomarker for certain diseases, making anti-S-100 α chain antibody (4c4.9) a valuable tool for researchers studying cellular mechanisms and disease states.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
S-100 α chain Antibody (4c4.9) | sc-58837 | 50 µg/0.5 ml | $322.00 |