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Rubrofusarin (CAS 3567-00-8)

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Application:
Rubrofusarin is an inhibitor of RNA Polymerase and Tyrosinase
CAS Number:
3567-00-8
Purity:
≥98%
Molecular Weight:
272.3
Molecular Formula:
C15H12O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Rubrofusarin is a monomer of aurofusarin. It is a mycotoxin that acts as a RNA polymerase inhibitor. This product is a potential anticancer and antimycobacterial compound. Additonally, it acts as a moderate tyrosinase inhibitor. It also has anti-estrogenic properties.


Rubrofusarin (CAS 3567-00-8) References

  1. Alaternin, cassiaside and rubrofusarin gentiobioside, radical scavenging principles from the seeds of Cassia tora on 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical.  |  Choi, JS., et al. 1994. Arch Pharm Res. 17: 462-6. PMID: 10319159
  2. A rubrofusarin gentiobioside isomer from roastedCassia tora.  |  Lee, HJ., et al. 1997. Arch Pharm Res. 20: 513-5. PMID: 18982501
  3. [Rubrofusarin glucosides of Berchemia polyphylla var. leioclada and their scavenging activities for DPPH radical].  |  Jing, Y., et al. 2011. Zhongguo Zhong Yao Za Zhi. 36: 2084-7. PMID: 22066444
  4. Reconstruction of the biosynthetic pathway for the core fungal polyketide scaffold rubrofusarin in Saccharomyces cerevisiae.  |  Rugbjerg, P., et al. 2013. Microb Cell Fact. 12: 31. PMID: 23557488
  5. Identification and Determination of Rubrofusarin, Rubrofusarin Isomer, and Their Quinone Forms in Grains Using High-Resolution Mass Spectrometry.  |  Wang, SS., et al. 2018. ACS Omega. 3: 15924-15932. PMID: 30556018
  6. Rubrofusarin-6-β-gentiobioside inhibits lipid accumulation and weight gain by regulating AMPK/mTOR signaling.  |  Han, YH., et al. 2019. Phytomedicine. 62: 152952. PMID: 31132754
  7. Rubrofusarin inhibits Aβ aggregation and ameliorates memory loss in an Aβ-induced Alzheimer's disease-like mouse model.  |  Cho, E., et al. 2019. Food Chem Toxicol. 132: 110698. PMID: 31348966
  8. Rubrofusarin as a Dual Protein Tyrosine Phosphate 1B and Human Monoamine Oxidase-A Inhibitor: An in Vitro and in Silico Study.  |  Paudel, P., et al. 2019. ACS Omega. 4: 11621-11630. PMID: 31460269
  9. Rubrofusarin Attenuates Chronic Restraint Stress-Induced Depressive Symptoms.  |  Yi, JH., et al. 2020. Int J Mol Sci. 21: PMID: 32414166
  10. Role of extracellular signal-regulated kinase in rubrofusarin-enhanced cognitive functions and neurite outgrowth.  |  Jeon, J., et al. 2022. Biomed Pharmacother. 147: 112663. PMID: 35093759
  11. Theoretical modelling of structure, vibrational and UV-vis absorbance spectra of rubrofusarin molecule.  |  Pankin, D., et al. 2023. Spectrochim Acta A Mol Biomol Spectrosc. 293: 122469. PMID: 36801731
  12. Metabolic products of fungi. XXV. Synthesis of rubrofusarin and its derivatives.  |  Shibata, S., et al. 1967. Chem Pharm Bull (Tokyo). 15: 1757-64. PMID: 5583835
  13. Chemical studies on the oriental plant drugs. XXI. The constituents of Cassia tora L. 2. A glycoside of rubrofusarin.  |  Kaneda, M., et al. 1969. Chem Pharm Bull (Tokyo). 17: 458-61. PMID: 5792305

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Rubrofusarin, 5 mg

sc-364132
5 mg
$460.00