Rubella Virus capsid protein Antibody (9B11): sc-65935

Rubella Virus capsid protein Antibody (9B11) is a mouse monoclonal IgG1 antibody that detects Rubella Virus capsid protein of rubella virus origin by western blotting (WB). Anti-Rubella Virus capsid protein antibody (9B11) is available as the non-conjugated format. Rubella Virus capsid protein plays a crucial role in the virus′s life cycle, primarily by facilitating viral RNA encapsidation and ensuring viral particle stability. Rubella Virus capsid protein is essential for infectious virion assembly and release, making Rubella Virus capsid protein a key target for therapeutic interventions and vaccine development. Rubella Virus capsid protein interacts with host cell machinery during viral replication, underscoring its importance in rubella pathogenesis. Notably, Rubella Virus capsid protein phosphorylation, while not directly influencing viral RNA and protein synthesis, is critical for early virus replication events, such as virion uncoating and nucleocapsid disassembly. Understanding these interactions and modifications can provide insights into potential antiviral strategies and effective vaccine development against rubella.

Alexa Fluor^® is a trademark of Molecular Probes Inc., OR., USA

LI-COR^® and Odyssey^® are registered trademarks of LI-COR Biosciences

Rubella Virus capsid protein Antibody (9B11) References:

1. Characterization of the zinc binding activity of the rubella virus nonstructural protease.  |  Liu, X., et al. 2000. J Virol. 74: 5949-56. PMID: 10846076
2. Mutations in the E1 hydrophobic domain of rubella virus impair virus infectivity but not virus assembly.  |  Qiu, Z., et al. 2000. J Virol. 74: 6637-42. PMID: 10864678
3. Evaluation of antibodies against a rubella virus neutralizing domain for determination of immune status.  |  Cordoba, P., et al. 2000. Clin Diagn Lab Immunol. 7: 964-6. PMID: 11063507
4. Localization of the virus neutralizing and hemagglutinin epitopes of E1 glycoprotein of rubella virus.  |  Chaye, H., et al. 1992. Virology. 189: 483-92. PMID: 1379391
5. Rubella virus capsid protein modulation of viral genomic and subgenomic RNA synthesis.  |  Tzeng, WP. and Frey, TK. 2005. Virology. 337: 327-34. PMID: 15907967
6. Phylogenetic analysis of envelope glycoprotein (E1) gene of rubella viruses prevalent in Japan in 2004.  |  Saitoh, M., et al. 2006. Microbiol Immunol. 50: 179-85. PMID: 16547415
7. Analyses of phosphorylation events in the rubella virus capsid protein: role in early replication events.  |  Law, LJ., et al. 2006. J Virol. 80: 6917-25. PMID: 16809297
8. Rubella virus capsid protein interacts with poly(a)-binding protein and inhibits translation.  |  Ilkow, CS., et al. 2008. J Virol. 82: 4284-94. PMID: 18305028
9. Rubella virus capsid protein: a small protein with big functions.  |  Ilkow, CS., et al. 2010. Future Microbiol. 5: 571-84. PMID: 20353299
10. A model of the structural organization of rubella virions.  |  Waxham, MN. and Wolinsky, JS. 1985. Rev Infect Dis. 7 Suppl 1: S133-9. PMID: 4001720
11. Identification of the rubella virus nonstructural proteins.  |  Forng, RY. and Frey, TK. 1995. Virology. 206: 843-53. PMID: 7856097
12. Sequence variation in 5' termini of rubella virus genomes: changes affecting structure of the 5' proximal stem-loop.  |  Johnstone, P., et al. 1996. Arch Virol. 141: 2471-7. PMID: 9526551