

Rtn-2 Antibody (PL-A9) is a mouse monoclonal IgG2a antibody that detects RTN2 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). RTN2, a member of the Reticulon family, plays a crucial role in the formation and maintenance of the endoplasmic reticulum′s structure, which is essential for proper cellular function and protein synthesis. RTN2 is primarily localized in the endoplasmic reticulum membranes, where RTN2 contributes to the shaping of the organelle and is involved in processes such as apoptosis and neurogenesis. Disruptions in RTN2 function or localization can lead to various diseases, including neurodegenerative disorders. RTN2 is encoded by a gene located on human chromosome 19q13, which produces three isoforms through alternative initiation sites and splicing, with RTN2-A and RTN2-B being predominantly expressed in the brain, while RTN2-C is mainly found in skeletal muscle. Anti-RTN2 antibody (PL-A9) is an invaluable tool for researchers studying the dynamics of the endoplasmic reticulum and its implications in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Rtn-2 Antibody (PL-A9) | sc-134431 | 100 µg/ml | $339.00 |